LOCUS SIT99976.1 271 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE GLUTAMATE RACEMASE MURI protein. ACCESSION LT708304-1388 PROTEIN_ID SIT99976.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="murI" /locus_tag="BQ2027_MB1373" /note="Mb1373, murI, len: 271 aa. Equivalent to Rv1338, len: 271 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 271 aa overlap). Probable murI, glutamate racemase (EC 5.1.1.3), highly similar to many e.g. MURI_MYCLE|P46705 (272 aa), FASTA scores: opt: 1559, E(): 0, (88.9% identity in 271 aa overlap). Contains PS00924 Aspartate and glutamate racemases signature 2. Protein product from Mb1373 detected using SWATH mass spectrometry. Mb1373 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P63636" /db_xref="InterPro:IPR001920" /db_xref="InterPro:IPR004391" /db_xref="InterPro:IPR015942" /db_xref="InterPro:IPR018187" /db_xref="InterPro:IPR033134" /db_xref="UniProtKB/Swiss-Prot:P63636" BEGIN 1 MNSPLAPVGV FDSGVGGLTV ARAIIDQLPD EDIVYVGDTG NGPYGPLTIP EIRAHALAIG 61 DDLVGRGVKA LVIACNSASS ACLRDARERY QVPVVEVILP AVRRAVAATR NGRIGVIGTR 121 ATITSHAYQD AFAAARDTEI TAVACPRFVD FVERGVTSGR QVLGLAQGYL EPLQRAEVDT 181 LVLGCTHYPL LSGLIQLAMG ENVTLVSSAE ETAKEVVRVL TEIDLLRPHD APPATRIFEA 241 TGDPEAFTKL AARFLGPVLG GVQPVHPSRI H //