LOCUS       SIT99976.1               271 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            GLUTAMATE RACEMASE MURI protein.
ACCESSION   LT708304-1388
PROTEIN_ID  SIT99976.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="murI"
                     /locus_tag="BQ2027_MB1373"
                     /note="Mb1373, murI, len: 271 aa. Equivalent to Rv1338,
                     len: 271 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 271 aa overlap). Probable murI,
                     glutamate racemase (EC 5.1.1.3), highly similar to many
                     e.g. MURI_MYCLE|P46705 (272 aa), FASTA scores: opt: 1559,
                     E(): 0, (88.9% identity in 271 aa overlap). Contains
                     PS00924 Aspartate and glutamate racemases signature 2.
                     Protein product from Mb1373 detected using SWATH mass
                     spectrometry. Mb1373 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P63636"
                     /db_xref="InterPro:IPR001920"
                     /db_xref="InterPro:IPR004391"
                     /db_xref="InterPro:IPR015942"
                     /db_xref="InterPro:IPR018187"
                     /db_xref="InterPro:IPR033134"
                     /db_xref="UniProtKB/Swiss-Prot:P63636"
BEGIN
        1 MNSPLAPVGV FDSGVGGLTV ARAIIDQLPD EDIVYVGDTG NGPYGPLTIP EIRAHALAIG
       61 DDLVGRGVKA LVIACNSASS ACLRDARERY QVPVVEVILP AVRRAVAATR NGRIGVIGTR
      121 ATITSHAYQD AFAAARDTEI TAVACPRFVD FVERGVTSGR QVLGLAQGYL EPLQRAEVDT
      181 LVLGCTHYPL LSGLIQLAMG ENVTLVSSAE ETAKEVVRVL TEIDLLRPHD APPATRIFEA
      241 TGDPEAFTKL AARFLGPVLG GVQPVHPSRI H
//