LOCUS SIT99962.1 304 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE THIOREDOXIN protein. ACCESSION LT708304-1374 PROTEIN_ID SIT99962.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1359" /note="Mb1359, -, len: 304 aa. Equivalent to Rv1324, len: 304 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 304 aa overlap). Possible thioredoxin (EC 1.-.-.-), similar to several e.g. U00014|Q49716 TRXA from Mycobacterium leprae (255 aa), FASTA scores: opt: 1014, E(): 0, (69.7% identity in 228 aa overlap); THIO_RHOSH|P08058 TrxA from Rhodobacter sphaeroides (105 aa), FASTA scores: opt 196, E(): 1.9e-06, (33.0% identity in 103 aa overlap). Contains PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. Protein product from Mb1359 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1359 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P64808" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="UniProtKB/Swiss-Prot:P64808" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTRPRPPLGP AMAGAVDLSG IKQRAQQNAA ASTDADRALS TPSGVTEITE ANFEDEVIVR 61 SDEVPVVVLL WSPRSEVCVD LLDTLSGLAA AAKGKWSLAS VNVDVAPRVA QIFGVQAVPT 121 VVALAAGQPI SSFQGLQPAD QLSRWVDSLL SATAGKLKGA ASSEESTEVD PAVAQARQQL 181 EDGDFVAARK SYQAILDANP GSVEAKAAIR QIEFLIRATA QRPDAVSVAD SLSDDIDAAF 241 AAADVQVLNQ DVSAAFERLI ALVRRTSGEE RTRVRTRLIE LFELFDPADP EVVAGRRNLA 301 NALY //