LOCUS       SIT99962.1               304 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            THIOREDOXIN protein.
ACCESSION   LT708304-1374
PROTEIN_ID  SIT99962.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1359"
                     /note="Mb1359, -, len: 304 aa. Equivalent to Rv1324, len:
                     304 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 304 aa overlap). Possible thioredoxin
                     (EC 1.-.-.-), similar to several e.g. U00014|Q49716 TRXA
                     from Mycobacterium leprae (255 aa), FASTA scores: opt:
                     1014, E(): 0, (69.7% identity in 228 aa overlap);
                     THIO_RHOSH|P08058 TrxA from Rhodobacter sphaeroides (105
                     aa), FASTA scores: opt 196, E(): 1.9e-06, (33.0% identity
                     in 103 aa overlap). Contains PS00339 Aminoacyl-transfer
                     RNA synthetases class-II signature 2. Protein product from
                     Mb1359 detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb1359 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P64808"
                     /db_xref="InterPro:IPR011990"
                     /db_xref="InterPro:IPR013766"
                     /db_xref="InterPro:IPR036249"
                     /db_xref="UniProtKB/Swiss-Prot:P64808"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTRPRPPLGP AMAGAVDLSG IKQRAQQNAA ASTDADRALS TPSGVTEITE ANFEDEVIVR
       61 SDEVPVVVLL WSPRSEVCVD LLDTLSGLAA AAKGKWSLAS VNVDVAPRVA QIFGVQAVPT
      121 VVALAAGQPI SSFQGLQPAD QLSRWVDSLL SATAGKLKGA ASSEESTEVD PAVAQARQQL
      181 EDGDFVAARK SYQAILDANP GSVEAKAAIR QIEFLIRATA QRPDAVSVAD SLSDDIDAAF
      241 AAADVQVLNQ DVSAAFERLI ALVRRTSGEE RTRVRTRLIE LFELFDPADP EVVAGRRNLA
      301 NALY
//