LOCUS       SIT99960.1               152 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Methylmalonyl-
            CoA epimerase (EC @ Ethylmalonyl-CoA epimerase protein.
ACCESSION   LT708304-1372
PROTEIN_ID  SIT99960.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1357C"
                     /EC_number="5.1.99.1"
                     /note="Mb1357c, -, len: 152 aa. Equivalent to Rv1322A,
                     len: 152 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 152 aa overlap). Conserved hypothetical
                     protein, similar to proteins from Mycobacterium leprae and
                     Streptomyces coelicolor e.g. AL583921_2|ML1157 from M.
                     leprae strain TN (155 aa), FASTA scores: opt: 771, E():
                     5.1e-43, (75.3% identity in 154 aa overlap); and
                     AL137242_2 from S. coelicolor (146 aa), FASTA scores: opt:
                     404, E(): 2e-19, (43.165% identity in 139 aa overlap).
                     Protein product from Mb1357c detected using shotgun mass
                     spectrometry. Mb1357c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR017515"
                     /db_xref="InterPro:IPR029068"
                     /db_xref="InterPro:IPR037523"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XY23"
BEGIN
        1 MMTTDQVHAR HMLATSLVTG LDHVGIAVAD LDVAIEWYHD HLGMILVHEE INDDQGIREA
       61 LLAVPGSAAQ IQLMAPLDES SVIAKFLDKR GPGIQQLACR VSDLDAMCRR LRSQGVRLVY
      121 ETARRGTANS RINFIHPKDA GGVLIELVEP AP
//