LOCUS SIT99958.1 226 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Endonuclease NucS protein. ACCESSION LT708304-1370 PROTEIN_ID SIT99958.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="nucS" /locus_tag="BQ2027_MB1355" /note="Mb1355, -, len: 226 aa. Equivalent to Rv1321, len: 226 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 226 aa overlap). Conserved hypothetical protein. Equivalent to P53524|YD21_MYCLE hypothetical protein from Mycobacterium leprae (201 aa), FASTA scores: opt: 1144, E(): 0, (87.6% identity in 193 aa overlap). Some similarity to hypothetical proteins from other organisms e.g. Y225_METJA|Q57678 Methanococcus jannaschii (263 aa), FASTA scores: E(): 6.5e-05, (25.0% identity in 212 aa overlap). Protein product from Mb1355 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1355 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P59979" /db_xref="InterPro:IPR002793" /db_xref="InterPro:IPR011856" /db_xref="UniProtKB/Swiss-Prot:P59979" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MSRVRLVIAQ CTVDYIGRLT AHLPSARRLL LFKADGSVSV HADDRAYKPL NWMSPPCWLT 61 EESGGQAPVW VVENKAGEQL RITIEGIEHD SSHELGVDPG LVKDGVEAHL QALLAEHIQL 121 LGEGYTLVRR EYMTAIGPVD LLCRDERGGS VAVEIKRRGE IDGVEQLTRY LELLNRDSVL 181 APVKGVFAAQ QIKPQARILA TDRGIRCLTL DYDTMRGMDS GEYRLF //