LOCUS       SIT99958.1               226 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Endonuclease
            NucS protein.
ACCESSION   LT708304-1370
PROTEIN_ID  SIT99958.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="nucS"
                     /locus_tag="BQ2027_MB1355"
                     /note="Mb1355, -, len: 226 aa. Equivalent to Rv1321, len:
                     226 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 226 aa overlap). Conserved hypothetical
                     protein. Equivalent to P53524|YD21_MYCLE hypothetical
                     protein from Mycobacterium leprae (201 aa), FASTA scores:
                     opt: 1144, E(): 0, (87.6% identity in 193 aa overlap).
                     Some similarity to hypothetical proteins from other
                     organisms e.g. Y225_METJA|Q57678 Methanococcus jannaschii
                     (263 aa), FASTA scores: E(): 6.5e-05, (25.0% identity in
                     212 aa overlap). Protein product from Mb1355 detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb1355 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P59979"
                     /db_xref="InterPro:IPR002793"
                     /db_xref="InterPro:IPR011856"
                     /db_xref="UniProtKB/Swiss-Prot:P59979"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSRVRLVIAQ CTVDYIGRLT AHLPSARRLL LFKADGSVSV HADDRAYKPL NWMSPPCWLT
       61 EESGGQAPVW VVENKAGEQL RITIEGIEHD SSHELGVDPG LVKDGVEAHL QALLAEHIQL
      121 LGEGYTLVRR EYMTAIGPVD LLCRDERGGS VAVEIKRRGE IDGVEQLTRY LELLNRDSVL
      181 APVKGVFAAQ QIKPQARILA TDRGIRCLTL DYDTMRGMDS GEYRLF
//