LOCUS       SIT99951.1               418 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA
            protein.
ACCESSION   LT708304-1363
PROTEIN_ID  SIT99951.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="murA"
                     /locus_tag="BQ2027_MB1348"
                     /note="Mb1348, murA, len: 418 aa. Equivalent to Rv1315,
                     len: 418 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 418 aa overlap). Probable murA,
                     UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC
                     2.5.1.7), highly similar to many e.g. MURA_MYCLE|P45821
                     (418 aa), FASTA scores: opt: 2495, E(): 0, (96.2% identity
                     in 396 aa overlap). BELONGS TO THE EPSP SYNTHASE FAMILY.
                     MURA SUBFAMILY. Protein product from Mb1348 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb1348 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P0A5L3"
                     /db_xref="InterPro:IPR001986"
                     /db_xref="InterPro:IPR005750"
                     /db_xref="InterPro:IPR013792"
                     /db_xref="InterPro:IPR036968"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5L3"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MAERFVVTGG NRLSGEVAVG GAKNSVLKLM AATLLAEGTS TITNCPDILD VPLMAEVLRG
       61 LGATVELDGD VARITAPDEP KYDADFAAVR QFRASVCVLG PLVGRCKRAR VALPGGDAIG
      121 SRPLDMHQAG LRQLGAHCNI EHGCVVARAE TLRGAEIQLE FPSVGATENI LMAAVVAEGV
      181 TTIHNAAREP DVVDLCTMLN QMGAQVEGAG SPTMTITGVP RLHPTEHRVI GDRIVAATWG
      241 IAAAMTRGDI SVAGVDPAHL QLVLHKLHDA GATVTQTDAS FRVTQYERPK AVNVATLPFP
      301 GFPTDLQPMA IALASIADGT SMITENVFEA RFRFVEEMIR LGADARTDGH HAVVRGLPQL
      361 SSAPVWCSDI RAGAGLVLAG LVADGDTEVH DVFHIDRGYP LFVENLVSLG AEIERVCC
//