LOCUS SIT99951.1 418 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA protein. ACCESSION LT708304-1363 PROTEIN_ID SIT99951.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="murA" /locus_tag="BQ2027_MB1348" /note="Mb1348, murA, len: 418 aa. Equivalent to Rv1315, len: 418 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 418 aa overlap). Probable murA, UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7), highly similar to many e.g. MURA_MYCLE|P45821 (418 aa), FASTA scores: opt: 2495, E(): 0, (96.2% identity in 396 aa overlap). BELONGS TO THE EPSP SYNTHASE FAMILY. MURA SUBFAMILY. Protein product from Mb1348 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1348 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P0A5L3" /db_xref="InterPro:IPR001986" /db_xref="InterPro:IPR005750" /db_xref="InterPro:IPR013792" /db_xref="InterPro:IPR036968" /db_xref="UniProtKB/Swiss-Prot:P0A5L3" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MAERFVVTGG NRLSGEVAVG GAKNSVLKLM AATLLAEGTS TITNCPDILD VPLMAEVLRG 61 LGATVELDGD VARITAPDEP KYDADFAAVR QFRASVCVLG PLVGRCKRAR VALPGGDAIG 121 SRPLDMHQAG LRQLGAHCNI EHGCVVARAE TLRGAEIQLE FPSVGATENI LMAAVVAEGV 181 TTIHNAAREP DVVDLCTMLN QMGAQVEGAG SPTMTITGVP RLHPTEHRVI GDRIVAATWG 241 IAAAMTRGDI SVAGVDPAHL QLVLHKLHDA GATVTQTDAS FRVTQYERPK AVNVATLPFP 301 GFPTDLQPMA IALASIADGT SMITENVFEA RFRFVEEMIR LGADARTDGH HAVVRGLPQL 361 SSAPVWCSDI RAGAGLVLAG LVADGDTEVH DVFHIDRGYP LFVENLVSLG AEIERVCC //