LOCUS       SIT99949.1               205 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            TRANSPOSASE [FIRST PART] protein.
ACCESSION   LT708304-1361
PROTEIN_ID  SIT99949.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1346C"
                     /note="Mb1346c, -, len: 205 aa. Equivalent to 5' end of
                     Rv1313c, len: 444 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (99.5% identity in 195 aa overlap). Possible
                     IS1557 transposase, similar to several transposases e.g.
                     U57649|DBU57649 ORF1 from dibenzofuran-degrading bacterium
                     DPO360 (163 aa), FASTA scores: opt: 767, E(): 0, (67.3%
                     identity in 168 aa overlap); TNPA_BORPA|Q06126 transposase
                     for insertion sequence element IS1001 from Bordetella
                     parapertussis (406 aa), FASTA scores: opt: 254, E():
                     3.3e-10, (24.9% identity in 402 aa overlap). Also similar
                     to putative Mycobacterium tuberculosis transposases,
                     Rv3798 and Rv0741. REMARK-M.bovis-M.tuberculosis: In
                     Mycobacterium tuberculosis strain H37Rv, Rv1313c exists as
                     a single gene. In Mycobacterium bovis, a frameshift due to
                     a 12 bp to 1 bp substitution (cttgtcgtggcc-t) splits
                     Rv1313c into 2 parts, Mb1345c and Mb1346c. Mb1346c found
                     to be expressed during exponential growth in Sauton's
                     minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR002560"
                     /db_xref="InterPro:IPR029261"
                     /db_xref="InterPro:IPR032877"
                     /db_xref="UniProtKB/TrEMBL:A0A0G2QBZ2"
BEGIN
        1 MRNVRLFRAL LGVDKRTVIE DIEFEEDDAG DGARVIARVR PRSAVLRRCG RCGRKASWYD
       61 RGAGLRQWRS LDWGTVEVFL EAEAPRVNCP THGPTVVAVP WARHHAGHTY AFDDTVAWLA
      121 VACSKTAVCE LMRIAWRTVG AIVARVWADT EKRIDRFANL RRIGIDEISY KRHHRYLTVV
      181 VDHDSGRLVW AAPSHPGLVL RCPGR
//