LOCUS       SIT99939.1               250 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ATP SYNTHASE A CHAIN ATPB (PROTEIN 6) protein.
ACCESSION   LT708304-1351
PROTEIN_ID  SIT99939.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="atpB"
                     /locus_tag="BQ2027_MB1336"
                     /note="Mb1336, atpB, len: 250 aa. Equivalent to Rv1304,
                     len: 250 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 250 aa overlap). Probable atpB, ATP
                     synthase A chain (EC 3.6.3.14), highly similar to
                     ATP6_MYCLE|P45829 Mycobacterium leprae (251 aa), FASTA
                     scores: opt: 1382, E(): 0, (84.0% identity in 250 aa
                     overlap). Contains PS00449 ATP synthase A subunit
                     signature. SUBUNIT: F-TYPE ATPASES HAVE 2 COMPONENTS,
                     CF(1) - THE CATALYTIC CORE - AND CF(0) - THE MEMBRANE
                     PROTON CHANNEL. CF(1) HAS FIVE SUBUNITS: ALPHA(3),
                     BETA(3), GAMMA(1), DELTA(1), EPSILON(1). CF(0) HAS THREE
                     MAIN SUBUNITS: A, B AND C. BELONGS TO THE ATPASE A CHAIN
                     FAMILY. Protein product from Mb1336 detected using shotgun
                     mass spectrometry and SWATH mass spectrometry. Mb1336
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P63655"
                     /db_xref="InterPro:IPR000568"
                     /db_xref="InterPro:IPR023011"
                     /db_xref="InterPro:IPR035908"
                     /db_xref="UniProtKB/Swiss-Prot:P63655"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTETILAAQI EVGEHHTATW LGMTVNTDTV LSTAIAGLIV IALAFYLRAK VTSTDVPGGV
       61 QLFFEAITIQ MRNQVESAIG MRIAPFVLPL AVTIFVFILI SNWLAVLPVQ YTDKHGHTTE
      121 LLKSAAADIN YVLALALFVF VCYHTAGIWR RGIVGHPIKL LKGHVTLLAP INLVEEVAKP
      181 ISLSLRLFGN IFAGGILVAL IALFPPYIMW APNAIWKAFD LFVGAIQAFI FALLTILYFS
      241 QAMELEEEHH
//