LOCUS SIT99932.1 602 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSCRIPTION TERMINATION FACTOR RHO HOMOLOG protein. ACCESSION LT708304-1344 PROTEIN_ID SIT99932.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="rho" /locus_tag="BQ2027_MB1329" /note="Mb1329, rho, len: 602 aa. Equivalent to Rv1297, len: 602 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 602 aa overlap). Probable rho, transcription termination factor homolog, highly similar to many e.g. RHO_MYCLE|P45835 Mycobacterium leprae (610 aa), FASTA scores: (81.5% identity in 612 aa overlap). CONTAINS 1 RNA RECOGNITION MOTIF (RRM). Protein product from Mb1329 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1329 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P66029" /db_xref="InterPro:IPR000194" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004665" /db_xref="InterPro:IPR011112" /db_xref="InterPro:IPR011113" /db_xref="InterPro:IPR011129" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036269" /db_xref="InterPro:IPR041703" /db_xref="UniProtKB/Swiss-Prot:P66029" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTDTDLITAG ESTDGKPSDA AATDPPDLNA DEPAGSLATM VLPELRALAN RAGVKGTSGM 61 RKNELIAAIE EIRRQANGAP AVDRSAQEHD KGDRPPSSEA PATQGEQTPT EQIDSQSQQV 121 RPERRSATRE AGPSGSGERA GTAADDTDNR QGGQQDAKTE ERGTDAGGDQ GGDQQASGGQ 181 QARGDEDGEA RQGRRGRRFR DRRRRGERSG DGAEAELRED DVVQPVAGIL DVLDNYAFVR 241 TSGYLPGPHD VYVSMNMVRK NGMRRGDAVT GAVRVPKEGE QPNQRQKFNP LVRLDSINGG 301 SVEDAKKRPE FGKLTPLYPN QRLRLETSTE RLTTRVIDLI MPIGKGQRAL IVSPPKAGKT 361 TILQDIANAI TRNNPECHLM VVLVDERPEE VTDMQRSVKG EVIASTFDRP PSDHTSVAEL 421 AIERAKRLVE QGKDVVVLLD SITRLGRAYN NASPASGRIL SGGVDSTALY PPKRFLGAAR 481 NIEEGGSLTI IATAMVETGS TGDTVIFEEF KGTGNAELKL DRKIAERRVF PAVDVNPSGT 541 RKDELLLSPD EFAIVHKLRR VLSGLDSHQA IDLLMSQLRK TKNNYEFLVQ VSKTTPGSMD 601 SD //