LOCUS       SIT99932.1               602 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTION TERMINATION FACTOR RHO HOMOLOG protein.
ACCESSION   LT708304-1344
PROTEIN_ID  SIT99932.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="rho"
                     /locus_tag="BQ2027_MB1329"
                     /note="Mb1329, rho, len: 602 aa. Equivalent to Rv1297,
                     len: 602 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 602 aa overlap). Probable rho,
                     transcription termination factor homolog, highly similar
                     to many e.g. RHO_MYCLE|P45835 Mycobacterium leprae (610
                     aa), FASTA scores: (81.5% identity in 612 aa overlap).
                     CONTAINS 1 RNA RECOGNITION MOTIF (RRM). Protein product
                     from Mb1329 detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb1329 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P66029"
                     /db_xref="InterPro:IPR000194"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR004665"
                     /db_xref="InterPro:IPR011112"
                     /db_xref="InterPro:IPR011113"
                     /db_xref="InterPro:IPR011129"
                     /db_xref="InterPro:IPR012340"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR036269"
                     /db_xref="InterPro:IPR041703"
                     /db_xref="UniProtKB/Swiss-Prot:P66029"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTDTDLITAG ESTDGKPSDA AATDPPDLNA DEPAGSLATM VLPELRALAN RAGVKGTSGM
       61 RKNELIAAIE EIRRQANGAP AVDRSAQEHD KGDRPPSSEA PATQGEQTPT EQIDSQSQQV
      121 RPERRSATRE AGPSGSGERA GTAADDTDNR QGGQQDAKTE ERGTDAGGDQ GGDQQASGGQ
      181 QARGDEDGEA RQGRRGRRFR DRRRRGERSG DGAEAELRED DVVQPVAGIL DVLDNYAFVR
      241 TSGYLPGPHD VYVSMNMVRK NGMRRGDAVT GAVRVPKEGE QPNQRQKFNP LVRLDSINGG
      301 SVEDAKKRPE FGKLTPLYPN QRLRLETSTE RLTTRVIDLI MPIGKGQRAL IVSPPKAGKT
      361 TILQDIANAI TRNNPECHLM VVLVDERPEE VTDMQRSVKG EVIASTFDRP PSDHTSVAEL
      421 AIERAKRLVE QGKDVVVLLD SITRLGRAYN NASPASGRIL SGGVDSTALY PPKRFLGAAR
      481 NIEEGGSLTI IATAMVETGS TGDTVIFEEF KGTGNAELKL DRKIAERRVF PAVDVNPSGT
      541 RKDELLLSPD EFAIVHKLRR VLSGLDSHQA IDLLMSQLRK TKNNYEFLVQ VSKTTPGSMD
      601 SD
//