LOCUS SIT99930.1 360 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 threonine synthase thrc (ts) protein. ACCESSION LT708304-1342 PROTEIN_ID SIT99930.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="thrC" /locus_tag="BQ2027_MB1327" /note="Mb1327, thrC, len: 360 aa. Equivalent to Rv1295, len: 360 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 360 aa overlap). Probable thrC, threonine synthase (EC 4.2.3.1) (see first citation below), highly similar to THRC_MYCLE|P45837 Mycobacterium leprae (360 aa), FASTA scores: opt: 2202, E(): 0, (93.9% identity in 359 aa overlap). Contains PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. Protein product from Mb1327 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1327 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P66903" /db_xref="InterPro:IPR000634" /db_xref="InterPro:IPR001926" /db_xref="InterPro:IPR004450" /db_xref="InterPro:IPR026260" /db_xref="InterPro:IPR036052" /db_xref="UniProtKB/Swiss-Prot:P66903" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTVPPTATHQ PWPGVIAAYR DRLPVGDDWT PVTLLEGGTP LIAATNLSKQ TGCTIHLKVE 61 GLNPTGSFKD RGMTMAVTDA LAHGQRAVLC ASTGNTSASA AAYAARAGIT CAVLIPQGKI 121 AMGKLAQAVM HGAKIIQIDG NFDDCLELAR KMAADFPTIS LVNSVNPVRI EGQKTAAFEI 181 VDVLGTAPDV HALPVGNAGN ITAYWKGYTE YHQLGLIDKL PRMLGTQAAG AAPLVLGEPV 241 SHPETIATAI RIGSPASWTS AVEAQQQSKG RFLAASDEEI LAAYHLVARV EGVFVEPASA 301 ASIAGLLKAI DDGWVARGST VVCTVTGNGL KDPDTALKDM PSVSPVPVDP VAVVEKLGLA //