LOCUS       SIT99917.1               325 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            OLIGOPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER
            OPPB protein.
ACCESSION   LT708304-1329
PROTEIN_ID  SIT99917.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="oppB"
                     /locus_tag="BQ2027_MB1314C"
                     /note="Mb1314c, oppB, len: 325 aa. Equivalent to Rv1283c,
                     len: 325 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 325 aa overlap). Probable oppB,
                     oligopeptide-transport integral membrane protein ABC
                     transporter (see citation below), similar to other
                     integral membrane proteins e.g. DPPB_ECOLI|P37316
                     dipeptide transport system permease protein from
                     Escherichia coli (339 aa), FASTA scores: opt: 402, E():
                     3.4e-20, (31.0% identity in 345 aa overlap); etc. Also
                     similar to Rv3665c|DppB probable peptide-transport
                     integral membrane protein from Mycobacterium tuberculosis.
                     Contains PS00402 Binding-protein-dependent transport
                     systems inner membrane comp signature. Protein product
                     from Mb1314c detected using SWATH mass spectrometry.
                     Mb1314c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P66967"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR035906"
                     /db_xref="UniProtKB/Swiss-Prot:P66967"
BEGIN
        1 MTRYLARRLL NYLVLLALAS FLTYCLTSLA FSPLESLMQR SPRPPQAVID AKAHDLGLDR
       61 PILARYANWV SHAVRGDFGT TITGQPVGTE LGRRIGVSLR LLVVGSVFGT VAGVVIGAWG
      121 AIRQYRLSDR VMTTLALLVL STPTFVVANL LILGALRVNW AVGIQLFDYT GETSPGVAGG
      181 VWDRLGDRLQ HLILPSLTLA LAAAAGFSRY QRNAMLDVLG QDFIRTARAK GLTRRRALLK
      241 HGLRTALIPM ATLFAYGVAG LVTGAVFVEK IFGWHGMGEW MVRGISTQDT NIVAAITVFS
      301 GAVVLLAGLL SDVIYAALDP RVRVS
//