LOCUS       SIT99916.1               291 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            OLIGOPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER
            OPPC protein.
ACCESSION   LT708304-1328
PROTEIN_ID  SIT99916.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="oppC"
                     /locus_tag="BQ2027_MB1313C"
                     /note="Mb1313c, oppC, len: 291 aa. Equivalent to Rv1282c,
                     len: 291 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 291 aa overlap). Probable oppC,
                     oligopeptide-transport integral membrane protein ABC
                     transporter (see citation below), similar to other
                     integral membrane proteins e.g. OPPC_ECOLI|P77664
                     oligopeptide transport system permease from Escherichia
                     coli (302 aa), FASTA scores: E(): 4.6e-33, (40.7% identity
                     in 275 aa overlap); etc. Also similar to Rv3664c|DPPC
                     probable peptide-transport integral membrane protein from
                     Mycobacterium tuberculosis. Mb1313c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P66965"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR025966"
                     /db_xref="InterPro:IPR035906"
                     /db_xref="UniProtKB/Swiss-Prot:P66965"
BEGIN
        1 MTEFASRRTL VVRRFLRNRA AVASLAALLL LFVSAYALPP LLPYSYDDLD FNALLQPPGT
       61 KHWLGTNALG QDLLAQTLRG MQKSMLIGVC VAVISTGIAA TVGAISGYFG GWRDRTLMWV
      121 VDLLLVVPSF ILIAIVTPRT KNSANIMFLV LLLAGFGWMI SSRMVRGMTM SLREREFIRA
      181 ARYMGVSSRR IIVGHVVPNV ASILIIDAAL NVAAAILAET GLSFLGFGIQ PPDVSLGTLI
      241 ADGTASATAF PWVFLFPASI LVLILVCANL TGDGLRDALD PASRSLRRGV R
//