LOCUS SIT99915.1 612 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE OLIGOPEPTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER OPPD protein. ACCESSION LT708304-1327 PROTEIN_ID SIT99915.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="oppD" /locus_tag="BQ2027_MB1312C" /note="Mb1312c, oppD, len: 612 aa. Equivalent to Rv1281c, len: 612 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 612 aa overlap). Probable oppD, oligopeptide-transport ATP-binding protein ABC transporter (see citation below), similar to others e.g. DPPD_BACSU|P26905 dipeptide transport ATP-binding protein from Bacillus subtilis (335 aa), FASTA scores: opt: 983, E(): 0, (48.6% identity in 319 aa overlap); etc. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop); 2 x PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS). Protein product from Mb1312c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1312c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P63396" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013563" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="UniProtKB/Swiss-Prot:P63396" BEGIN 1 MSPLLEVTDL AVTFRTDGDP VTAVRGISYR VEPGEVVAMV GESGSGKSAA AMAVVGLLPE 61 YAQVRGSVRL QGTELLGLAD NAMSRFRGKA IGTVFQDPMS ALTPVYTVGD QIAEAIEVHQ 121 PRVGKKAARR RAVELLDLVG ISQPQRRSRA FPHELSGGER QRVVIAIAIA NDPDLLICDE 181 PTTALDVTVQ AQILDVLKAA RDVTGAGVLI ITHDLGVVAE FADRALVMYA GRVVESAGVN 241 DLYRDRRMPY TVGLLGSVPR LDAAQGTRLV PIPGAPPSLA GLAPGCPFAP RCPLVIDECL 301 TAEPELLDVA TDHRAACIRT ELVTGRSAAD IYRVKTEARP AALGDASVVV RVRHLVKTYR 361 LAKGVVLRRA IGEVRAVDGI SLELRQGRTL GIVGESGSGK STTLHEILEL AAPQSGSIEV 421 LGTDVATLGT AERRSLRRDI QVVFQDPVAS LDPRLPVFDL IAEPLQANGF GKNETHARVA 481 ELLDIVGLRH GDASRYPAEF SGGQKQRIGI ARALALQPKI LALDEPVSAL DVSIQAGIIN 541 LLLDLQEQFG LSYLFVSHDL SVVKHLAHQV AVMLAGTVVE QGDSEEVFGN PKHEYTRRLL 601 GAVPQPDPAR RG //