LOCUS       SIT99912.1               875 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 DNA
            double-strand break repair Rad50 ATPase protein.
ACCESSION   LT708304-1324
PROTEIN_ID  SIT99912.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1309"
                     /note="Mb1309, -, len: 875 aa. Equivalent to Rv1278, len:
                     875 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 875 aa overlap). Hypothetical unknown
                     protein, possible coiled-coil regions, contains PS00017
                     ATP/GTP-binding site motif A. Protein product from Mb1309
                     detected using SWATH mass spectrometry. Mb1309 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR041685"
                     /db_xref="UniProtKB/Swiss-Prot:P64796"
BEGIN
        1 MKLHRLALTN YRGIAHRDVE FPDHGVVVVC GANEIGKSSM VEALDLLLEY KDRSTKKEVK
       61 QVKPTNADVG SEVIAEISSG PYRFVYRKRF HKRCETELTV LAPRREQLTG DEAHERVRTM
      121 LAETVDTELW HAQRVLQAAS TAAVDLSGCD ALSRALDLAA GDDAALSGTE SLLIERIEAE
      181 YARYFTPTGR PTGEWSAAVS RLAAAEAAVA DCAAAVAEVD DGVRRHTELT EQVAELSQQL
      241 LAHQLRLEAA RVAAEKIAAI TDDAREAKLI ATAAAATSGA STAAHAGRLG LLTEIDTRTA
      301 AVVAAEAKAR QAADEQATAR AEAEACDAAL TEATQVLTAV RLRAESARRT LDQLADCEEA
      361 DRLAARLARI DDIEGDRDRV CAELSAVTLT EELLSRIERA AAAVDRGGAQ LASISAAVEF
      421 TAAVDIELGV GDQRVSLSAG QSWSVTATGP TEVKVPGVLT ARIVPGATAL DFQAKYAAAQ
      481 QELADALAAG EVADLAAARS ADLCRRELLS RRDQLTATLA GLCGDEQVDQ LRSRLEQLCA
      541 GQPAELDLVS TDTATARAEL DAVEAARIAA EKDCETRRQI AAGAARRLAE TSTRATVLQN
      601 AAAAESAELG AAMTRLACER ASVGDDELAA KAEADLRVLQ TAEQRVIDLA DELAATAPDA
      661 VAAELAEAAD AVELLRERHD EAIRALHEVG VELSVFGTQG RKGKLDAAET EREHAASHHA
      721 RVGRRARAAR LLRSVMARHR DTTRLRYVEP YRAELHRLGR PVFGPSFEVE VDTDLRIRSR
      781 TLDDRTVPYE CLSGGAKEQL GILARLAGAA LVAKEDAVPV LIDDALGFTD PERLAKMGEV
      841 FDTIGADGQV IVLTCSPTRY GGVKGAHRID LDAIQ
//