LOCUS SIT99912.1 875 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 DNA double-strand break repair Rad50 ATPase protein. ACCESSION LT708304-1324 PROTEIN_ID SIT99912.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1309" /note="Mb1309, -, len: 875 aa. Equivalent to Rv1278, len: 875 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 875 aa overlap). Hypothetical unknown protein, possible coiled-coil regions, contains PS00017 ATP/GTP-binding site motif A. Protein product from Mb1309 detected using SWATH mass spectrometry. Mb1309 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR041685" /db_xref="UniProtKB/Swiss-Prot:P64796" BEGIN 1 MKLHRLALTN YRGIAHRDVE FPDHGVVVVC GANEIGKSSM VEALDLLLEY KDRSTKKEVK 61 QVKPTNADVG SEVIAEISSG PYRFVYRKRF HKRCETELTV LAPRREQLTG DEAHERVRTM 121 LAETVDTELW HAQRVLQAAS TAAVDLSGCD ALSRALDLAA GDDAALSGTE SLLIERIEAE 181 YARYFTPTGR PTGEWSAAVS RLAAAEAAVA DCAAAVAEVD DGVRRHTELT EQVAELSQQL 241 LAHQLRLEAA RVAAEKIAAI TDDAREAKLI ATAAAATSGA STAAHAGRLG LLTEIDTRTA 301 AVVAAEAKAR QAADEQATAR AEAEACDAAL TEATQVLTAV RLRAESARRT LDQLADCEEA 361 DRLAARLARI DDIEGDRDRV CAELSAVTLT EELLSRIERA AAAVDRGGAQ LASISAAVEF 421 TAAVDIELGV GDQRVSLSAG QSWSVTATGP TEVKVPGVLT ARIVPGATAL DFQAKYAAAQ 481 QELADALAAG EVADLAAARS ADLCRRELLS RRDQLTATLA GLCGDEQVDQ LRSRLEQLCA 541 GQPAELDLVS TDTATARAEL DAVEAARIAA EKDCETRRQI AAGAARRLAE TSTRATVLQN 601 AAAAESAELG AAMTRLACER ASVGDDELAA KAEADLRVLQ TAEQRVIDLA DELAATAPDA 661 VAAELAEAAD AVELLRERHD EAIRALHEVG VELSVFGTQG RKGKLDAAET EREHAASHHA 721 RVGRRARAAR LLRSVMARHR DTTRLRYVEP YRAELHRLGR PVFGPSFEVE VDTDLRIRSR 781 TLDDRTVPYE CLSGGAKEQL GILARLAGAA LVAKEDAVPV LIDDALGFTD PERLAKMGEV 841 FDTIGADGQV IVLTCSPTRY GGVKGAHRID LDAIQ //