LOCUS       SIT99900.1               588 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pknH2 protein.
ACCESSION   LT708304-1312
PROTEIN_ID  SIT99900.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pknH2"
                     /locus_tag="BQ2027_MB1297CB"
                     /note="Mb1297cB, PknH2, putative membrane spanning
                     serine/threonine protein kinase, part of RD900 first
                     identified in M. africanum GM041182(Bentley et al. 2012,
                     PLoS Negl Top Dis. http://www.ncbi.nlm.nih.gov/pubmed/
                     22389744). 555/567 (96%) identity with MAF_12870"
                     /db_xref="GOA:A0A1R3XXU5"
                     /db_xref="InterPro:IPR000719"
                     /db_xref="InterPro:IPR008271"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="InterPro:IPR017441"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXU5"
BEGIN
        1 MSAAAGWLGG SAMSDAQDSR VGSMFGPYHL KRLLGRGGMG EVYEAEHTVK EWTVAVKLMT
       61 AEFSKDPVFR ERMKREARIA GRLQEPHVVP IHDYGEVDGQ MFLEMRLVEG TDLDSVLKRF
      121 GPLTPPRAVA IITQIASALD AAHADGVMHR DVKPQNILIT RDDFAYLVDF GIASATTDEK
      181 LTQLGTAVGT WKYMAPERFS NDEVTYRADS LRAGLRAARM LDRGPAVSRR HAGTLVSSHL
      241 MGPIPQPSAI RPGIPKAFDA VVARGMAKKP EDRYASAGDL ALAAHEALSD PDQDHAADIL
      301 RRSQESTLPG TAAVTAQPPT MPTVTPPPIQ AAPTGQPSWA PNSGPMPASG PTPTPQYYQG
      361 GGWGAPPSGG PSPWAQTPRK TNPWPFVAVA AAVVLVLVLG AIGIWIANRP DDNPKRNIAT
      421 SPGTPTTTAT TSLPATTTPT TAPASDPQTR LLSMLPSGYP TGTCKPTTPK PNSIWVNAVA
      481 MVDCGQNTNQ GGPSRAIYGL FANPDKLKQA FNDDIAAVEL MNCPGEGPSP DGWHYNQTPD
      541 VTAGMIACGT YKNRPNVIWS NEAKLTLSDV FGDPATIEDL HNWWAKYG
//