LOCUS SIT99900.1 588 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 pknH2 protein. ACCESSION LT708304-1312 PROTEIN_ID SIT99900.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="pknH2" /locus_tag="BQ2027_MB1297CB" /note="Mb1297cB, PknH2, putative membrane spanning serine/threonine protein kinase, part of RD900 first identified in M. africanum GM041182(Bentley et al. 2012, PLoS Negl Top Dis. http://www.ncbi.nlm.nih.gov/pubmed/ 22389744). 555/567 (96%) identity with MAF_12870" /db_xref="GOA:A0A1R3XXU5" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR008271" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR017441" /db_xref="UniProtKB/TrEMBL:A0A1R3XXU5" BEGIN 1 MSAAAGWLGG SAMSDAQDSR VGSMFGPYHL KRLLGRGGMG EVYEAEHTVK EWTVAVKLMT 61 AEFSKDPVFR ERMKREARIA GRLQEPHVVP IHDYGEVDGQ MFLEMRLVEG TDLDSVLKRF 121 GPLTPPRAVA IITQIASALD AAHADGVMHR DVKPQNILIT RDDFAYLVDF GIASATTDEK 181 LTQLGTAVGT WKYMAPERFS NDEVTYRADS LRAGLRAARM LDRGPAVSRR HAGTLVSSHL 241 MGPIPQPSAI RPGIPKAFDA VVARGMAKKP EDRYASAGDL ALAAHEALSD PDQDHAADIL 301 RRSQESTLPG TAAVTAQPPT MPTVTPPPIQ AAPTGQPSWA PNSGPMPASG PTPTPQYYQG 361 GGWGAPPSGG PSPWAQTPRK TNPWPFVAVA AAVVLVLVLG AIGIWIANRP DDNPKRNIAT 421 SPGTPTTTAT TSLPATTTPT TAPASDPQTR LLSMLPSGYP TGTCKPTTPK PNSIWVNAVA 481 MVDCGQNTNQ GGPSRAIYGL FANPDKLKQA FNDDIAAVEL MNCPGEGPSP DGWHYNQTPD 541 VTAGMIACGT YKNRPNVIWS NEAKLTLSDV FGDPATIEDL HNWWAKYG //