LOCUS SIT99899.1 798 aa PRT BCT 25-MAY-2020
DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 tbd2 protein.
ACCESSION LT708304-1311
PROTEIN_ID SIT99899.1
SOURCE Mycobacterium tuberculosis variant bovis AF2122/97
ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Malone K.M.
JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine, University College
Dublin, D4, Ireland
REFERENCE 2
AUTHORS Malone M K., Farrell D., Malone K.
JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine,, University College
Dublin, D4, Ireland
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis variant bovis
AF2122/97"
/chromosome="Mycobacterium_bovis_AF212297"
/isolate="AF2122/97"
/mol_type="genomic DNA"
/isolation_source="Mycobacterium bovis subsp. bovis strain
AF2122/97. This strain is a fully virulent strain that was
isolated in 1997 in the UK from a cow suffering necrotic
lesions in lung and bronchomediastinal lymph nodes. The
strain was also reported to infect and persist in badgers
that are considered to be a significant source of bovine
infection."
/db_xref="taxon:233413"
protein /transl_table=11
/gene="tbd2"
/locus_tag="BQ2027_MB1297CA"
/note="Mb1297cA, Tbd2, putative intergral membrane,
ATP-binding, ABC transporter. Part of RD900 first
identified in M. africanum GM041182 (Bentley et al. 2012,
PLoS Negl Top Dis. http://www.ncbi.nlm.nih.gov/pubmed/
22389744). 797/798 (99%) AA identity with MAF_12860.
Misidentified in original M. bovis AF2122/97 genome
assembly. Mb1297cA found to be expressed during
exponential growth in Sauton's minimal media by
RNA-sequencing (TPM > 20)."
/db_xref="GOA:A0A1R3XXW0"
/db_xref="InterPro:IPR000253"
/db_xref="InterPro:IPR003439"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR008984"
/db_xref="InterPro:IPR013525"
/db_xref="InterPro:IPR027417"
/db_xref="UniProtKB/TrEMBL:A0A1R3XXW0"
BEGIN
1 MTDTADMITP NAPRLELRAA GRTWHAVAGR EWSIGRASEA DIRLDNPRVS RQHAVLEATP
61 EGWVLVNLST NGTFVDGQRV ERLTVRQPIT IFLGSASSGQ RVQLYPVAQS PTPTPASHPP
121 APPRPATPKP AQRQGETTVA RPPTAFHAID QLVVTIGRAP ENTVVLNDLL VSRRHAILRR
181 TGNRWELSDN ASANGTYVNG HRISRAVIGP TDIVGIGHQL LHLSADRLVE YVDTGDISYQ
241 ASNLRVVTNK GRVLLADVSF VLPQRSLLAV VGPSGAGKST LLGALTGFRP AGNGTVRYDE
301 RDLYDNYAEL RHRIGFVPQD DILHTPLTVR RALNYAARLR FPQDVSVDER NQRIEEVLVE
361 LGLSTQADQR IDSLSGGQRK RTSVALELLT KPSLLFLDEP TSGLDPGYEK SVMQTLRKLA
421 DDGRSVVVVT HNIAHLNMCD RLLILAPGGR LAYFGPPQQA LGYFNCTDFA DLFTLLEHDT
481 STDWTGRFNA SPLREALIGH PAMRPARPAA ARHARPVAQQ SAFAQFAILC RRYLAVIAAD
541 RQYAVFLLVL PLLLSLFAHA VPGQAGLSLA KAIELKSTQP SQLLVLLIIG GALMGCAASI
601 REIVKERAIY RREHGIGLSR GAYLASKLVV LTALTSLQAL ILGFLGVALL PPPDQSVILP
661 WPSVEVAVAV VAVTVVSMMI GLLISAMIGN ADRGMPLLVL VVMAQLVLCG GMFGVSGRPP
721 LEQLSWLSPS RWAYAMAAAT VDLNDLRRTA GGDQDPLWDY NVGSWLMAAG ACAVQALVLV
781 ILIALQLKRI EPQRKARK
//