LOCUS       SIT99894.1               144 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 HYPOTHETICAL
            HIT-LIKE PROTEIN protein.
ACCESSION   LT708304-1306
PROTEIN_ID  SIT99894.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1293C"
                     /note="Mb1293c, -, len: 144 aa. Equivalent to Rv1262c,
                     len: 144 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.3% identity in 144 aa overlap). Hypothetical HIT-like
                     protein, similar to Q04344|HIT_YEAST hit1 protein (orf u)
                     (144 aa), FASTA scores: opt: 306, E(): 3e-14, (35.9 %
                     identity in 142 aa overlap); also similar to
                     YHIT_MYCGE|P47378 hypothetical 15.6 kd protein (141 aa),
                     FASTA scores: opt: 250, E(): 1.6e-10, (35.5% identity in
                     107 aa overlap); and YHIT_MYCLE|P49774 hypothetical 17.0
                     kd protein hit-like (155 aa), FASTA scores: opt: 196, E():
                     7e-07, (30.6% identity in 144 aa overlap). Similar to
                     other proteins from Mycobacterium tuberculosis e.g.
                     Rv2613c, Rv0759c. Contains PS00892 HIT family signature.
                     BELONGS TO THE HIT FAMILY. Protein product from Mb1293c
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb1293c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XXU9"
                     /db_xref="InterPro:IPR001310"
                     /db_xref="InterPro:IPR011146"
                     /db_xref="InterPro:IPR019808"
                     /db_xref="InterPro:IPR036265"
                     /db_xref="InterPro:IPR039384"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXU9"
BEGIN
        1 MPCVFCAIIA GEAPAIRIYE DGGYLAILDI RPFTRGHTLV LPKRHTVDLT DTPPEALADM
       61 VAIGQRIARA ARATKLADAT HIAINDGRAA FQTVFHVHLH VLPRRNGDKL SVAKGMMLRR
      121 DPDREATGRI LREALAQQDA AAQD
//