LOCUS       SIT99887.1               383 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYLTRANSFERASE protein.
ACCESSION   LT708304-1299
PROTEIN_ID  SIT99887.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1286"
                     /note="Mb1286, -, len: 383 aa. Equivalent to Rv1254, len:
                     383 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 383 aa overlap). Probable
                     Acyltransferase (EC 2.3.1.-), similar to G927228
                     midecamycin 4-0-propionyl transferase (fragment) (388 aa),
                     FASTA scores, opt: 305, E(): 5.6e-14, (28.4% identity in
                     377 aa overlap). Also similar to other Mycobacterium
                     tuberculosis acyltransferases e.g. Rv0111, Rv0228, etc.
                     Contains PS00881 Protein splicing signature. Protein
                     product from Mb1286 detected using SWATH mass
                     spectrometry. Mb1286 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XXT3"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXT3"
BEGIN
        1 MTLPKERAAQ GGLERIAHVD RVASLTGIRA VAALLVVGTH AAYTTGKYTH GYWGLMSSRM
       61 EIGVPIFFVL SGFLLFRPWV KSAATGGPPP SLSRYAWHRV RRIMPAYTVT VLLAYLVYHF
      121 RTAGPNPGHT WVGLFRNLTL TQIYTDGYLG AFLHQGLTQM WSLAVEVAFY LALPALAYLL
      181 LVLVCRRRWQ PRLLLATMAG LTMISPAWLI LVHNTHWMPD GARLWLPTYL AWFVGGMMLA
      241 VLAAMGVRCY AFVAIPLAVI CYFIVSTPIA GAPTTSPTAL AEALVKTAFY AVIAVLAVAP
      301 LALGDQGWYA QLLASRPMVF LGEISYEIFL IHLVTMEIAM VDVLGYRVYT SSMVNLCLVT
      361 LVLTIPLAWL LHRFTRVQGD RPS
//