LOCUS SIT99887.1 383 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE ACYLTRANSFERASE protein. ACCESSION LT708304-1299 PROTEIN_ID SIT99887.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1286" /note="Mb1286, -, len: 383 aa. Equivalent to Rv1254, len: 383 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 383 aa overlap). Probable Acyltransferase (EC 2.3.1.-), similar to G927228 midecamycin 4-0-propionyl transferase (fragment) (388 aa), FASTA scores, opt: 305, E(): 5.6e-14, (28.4% identity in 377 aa overlap). Also similar to other Mycobacterium tuberculosis acyltransferases e.g. Rv0111, Rv0228, etc. Contains PS00881 Protein splicing signature. Protein product from Mb1286 detected using SWATH mass spectrometry. Mb1286 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XXT3" /db_xref="InterPro:IPR002656" /db_xref="UniProtKB/TrEMBL:A0A1R3XXT3" BEGIN 1 MTLPKERAAQ GGLERIAHVD RVASLTGIRA VAALLVVGTH AAYTTGKYTH GYWGLMSSRM 61 EIGVPIFFVL SGFLLFRPWV KSAATGGPPP SLSRYAWHRV RRIMPAYTVT VLLAYLVYHF 121 RTAGPNPGHT WVGLFRNLTL TQIYTDGYLG AFLHQGLTQM WSLAVEVAFY LALPALAYLL 181 LVLVCRRRWQ PRLLLATMAG LTMISPAWLI LVHNTHWMPD GARLWLPTYL AWFVGGMMLA 241 VLAAMGVRCY AFVAIPLAVI CYFIVSTPIA GAPTTSPTAL AEALVKTAFY AVIAVLAVAP 301 LALGDQGWYA QLLASRPMVF LGEISYEIFL IHLVTMEIAM VDVLGYRVYT SSMVNLCLVT 361 LVLTIPLAWL LHRFTRVQGD RPS //