LOCUS SIT99872.1 366 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE MAGNESIUM AND COBALT TRANSPORT TRANSMEMBRANE PROTEIN CORA protein. ACCESSION LT708304-1284 PROTEIN_ID SIT99872.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="corA" /locus_tag="BQ2027_MB1271C" /note="Mb1271c, corA, len: 366 aa. Equivalent to Rv1239c, len: 366 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 366 aa overlap). Possible corA, magnesium and cobalt transport transmembrane protein, highly similar to U15180 corA protein from Mycobacterium leprae (373 aa), FASTA scores: opt: 1985, E(): 0, (79.1% identity in 369 aa overlap). Also similar to various CorA proteins of Gram negative bacteria e.g. P27841|CORA_ECOLI|B3816|Z5333|ECS4746 Magnesium and cobalt transport protein from Escherichia coli strains K12 and O157:H7 (316 aa), FASTA scores: opt: 236, E(): 8e-08, (24.5% identity in 306 aa overlap); etc. SEEMS TO BELONG TO THE MIT FAMILY. Protein product from Mb1271c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1271c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZW9" /db_xref="InterPro:IPR002523" /db_xref="InterPro:IPR004488" /db_xref="UniProtKB/TrEMBL:A0A1R3XZW9" BEGIN 1 MFPGFDALPE VLRPVARPQP PNAHPVAQPP AQALVDCGVY VCGQRLPGKY TYAAALREVR 61 EIELTGQEAF VWIGLHEPDE NQMQDVADVF GLHPLAVEDA VHAHQRPKLE RYDETLFLVL 121 KTVNYVPHES VVLAREIVET GEIMIFVGKD FVVTVRHGEH GGLSEVRKRM DADPEHLRLG 181 PYAVMHAIAD YVVDRYLEVT NLMETDIDSI EEVAFAPGRK LDIEPIYLLK REVVELRRCV 241 NPLSTAFQRM QTESKDLISK EVRRYLRDVA DHQTEAADQI ASYDDMLNSL VQAALARVGM 301 QQNMDMRKIS AWAGIIAVPT MIAGIYGMNF HFMPELDSRW GYPTVIGGMV LICLFLYHVF 361 RNRNWL //