LOCUS SIT99862.1 390 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE MRP-RELATED PROTEIN MRP protein. ACCESSION LT708304-1274 PROTEIN_ID SIT99862.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="mrp" /locus_tag="BQ2027_MB1261C" /note="Mb1261c, mrp, len: 390 aa. Equivalent to Rv1229c, len: 390 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 390 aa overlap). Probable Mrp protein, similar to others e.g. MRP_ECOLI|P21590 mrp protein from Escherichia coli (379 aa), FASTA scores: E(): 0, (34.1% identity in 355 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop); and PS01215 MRP Prosite domain. BELONGS TO THE MRP/NBP35 FAMILY OF ATP-BINDING PROTEINS. Protein product from Mb1261c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1261c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P65442" /db_xref="InterPro:IPR000808" /db_xref="InterPro:IPR002744" /db_xref="InterPro:IPR019591" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR033756" /db_xref="InterPro:IPR034904" /db_xref="UniProtKB/Swiss-Prot:P65442" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MPSRLHSAVM SGTRDGDLNA AIRTALGKVI DPELRRPITE LGMVKSIDTG PDGSVHVEIY 61 LTIAGCPKKS EITERVTRAV ADVPGTSAVR VSLDVMSDEQ RTELRKQLRG DTREPVIPFA 121 QPDSLTRVYA VASGKGGVGK STVTVNLAAA MAVRGLSIGV LDADIHGHSI PRMMGTTDRP 181 TQVESMILPP IAHQVKVISI AQFTQGNTPV VWRGPMLHRA LQQFLADVYW GDLDVLLLDL 241 PPGTGDVAIS VAQLIPNAEL LVVTTPQLAA AEVAERAGSI ALQTRQRIVG VVENMSGLTL 301 PDGTTMQVFG EGGGRLVAER LSRAVGADVP LLGQIPLDPA LVAAGDSGVP LVLSSPDSAI 361 GKELHSIADG LSTRRRGLAG MSLGLDPTRR //