LOCUS       SIT99862.1               390 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            MRP-RELATED PROTEIN MRP protein.
ACCESSION   LT708304-1274
PROTEIN_ID  SIT99862.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mrp"
                     /locus_tag="BQ2027_MB1261C"
                     /note="Mb1261c, mrp, len: 390 aa. Equivalent to Rv1229c,
                     len: 390 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 390 aa overlap). Probable Mrp protein,
                     similar to others e.g. MRP_ECOLI|P21590 mrp protein from
                     Escherichia coli (379 aa), FASTA scores: E(): 0, (34.1%
                     identity in 355 aa overlap). Contains PS00017
                     ATP/GTP-binding site motif A (P-loop); and PS01215 MRP
                     Prosite domain. BELONGS TO THE MRP/NBP35 FAMILY OF
                     ATP-BINDING PROTEINS. Protein product from Mb1261c
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb1261c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P65442"
                     /db_xref="InterPro:IPR000808"
                     /db_xref="InterPro:IPR002744"
                     /db_xref="InterPro:IPR019591"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR033756"
                     /db_xref="InterPro:IPR034904"
                     /db_xref="UniProtKB/Swiss-Prot:P65442"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MPSRLHSAVM SGTRDGDLNA AIRTALGKVI DPELRRPITE LGMVKSIDTG PDGSVHVEIY
       61 LTIAGCPKKS EITERVTRAV ADVPGTSAVR VSLDVMSDEQ RTELRKQLRG DTREPVIPFA
      121 QPDSLTRVYA VASGKGGVGK STVTVNLAAA MAVRGLSIGV LDADIHGHSI PRMMGTTDRP
      181 TQVESMILPP IAHQVKVISI AQFTQGNTPV VWRGPMLHRA LQQFLADVYW GDLDVLLLDL
      241 PPGTGDVAIS VAQLIPNAEL LVVTTPQLAA AEVAERAGSI ALQTRQRIVG VVENMSGLTL
      301 PDGTTMQVFG EGGGRLVAER LSRAVGADVP LLGQIPLDPA LVAAGDSGVP LVLSSPDSAI
      361 GKELHSIADG LSTRRRGLAG MSLGLDPTRR
//