LOCUS SIT99860.1 177 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSMEMBRANE PROTEIN protein. ACCESSION LT708304-1272 PROTEIN_ID SIT99860.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1259C" /note="Mb1259c, -, len: 177 aa. Equivalent to Rv1227c, len: 177 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 177 aa overlap). Possible transmembrane protein, similar to P96615 hypothetical protein ydbS from Bacillus subtilis (159 aa), fasta scores: E(): 3.6e-07, (30.1% identity in 163 aa overlap). Protein product from Mb1259c detected using SWATH mass spectrometry. Mb1259c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XXQ6" /db_xref="InterPro:IPR005182" /db_xref="UniProtKB/TrEMBL:A0A1R3XXQ6" BEGIN 1 MDHARNVPSA TGPQRNHLAL AEPAHRPSSQ APVMWALSAS LGWILPVIAQ LVWWAVHPQP 61 PWPHLAAAAL TAVAMVVHIG VVPLWRYRVH RWEISPQAVF TRTGWLVQER RITPISRVQT 121 VDTYRGPMDR LFGLANVTVT TASSAGAVHI EALDTDVADR VVAQLTDIAA LRGEDAT //