LOCUS       SIT99852.1               212 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN protein.
ACCESSION   LT708304-1264
PROTEIN_ID  SIT99852.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1251C"
                     /note="Mb1251c, -, len: 212 aa. Equivalent to Rv1219c,
                     len: 212 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 212 aa overlap). Probable
                     transcriptional regulatory protein, some similarity in
                     N-terminus to YBIH_ECOLI|P41037 hypothetical
                     transcriptional regulator from Escherichia coli (103 aa),
                     FASTA scores: opt: 143, E(): 8.9e-06, (39.7% identity in
                     63 aa overlap); Helix turn helix motif from aa 28-49.
                     Protein product from Mb1251c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1251c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XZU0"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR036271"
                     /db_xref="InterPro:IPR041484"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZU0"
BEGIN
        1 MRSADLTAHA RIREAAIEQF GRHGFGVGLR AIAEAAGVSA ALVIHHFGSK EGLRKACDDF
       61 VAEEIRSSKA AALKSNDPTT WLAQMAEIES YAPLMAYLVR SMQSGGELAK MLWQKMIDNA
      121 EEYLDEGVRA GTVKPSRDPR ARARFLAITG GGGFLLYLQM HENPTDLRAA LRDYAHDMVL
      181 PSLEVYTEGL LADRAMYEAF LAEAQQGEAH VG
//