LOCUS       SIT99851.1               311 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TETRONASIN-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER
            protein.
ACCESSION   LT708304-1263
PROTEIN_ID  SIT99851.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1250C"
                     /note="Mb1250c, -, len: 311 aa. Equivalent to Rv1218c,
                     len: 311 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 311 aa overlap). Probable
                     tetronasin-transport ATP-binding protein ABC transporter
                     (see citation below), similar to many e.g.
                     Q54406|X73633|TNRB2 TNRB2 PROTEIN from Streptomyces
                     longisporoflavus (300 aa), FASTA scores: opt: 1133, E():
                     0, (60.8% identity in 291 aa overlap); etc. Also similar
                     to others in Mycobacterium tuberculosis e.g. MTCY19H9.04
                     (30.0% identity in 297 aa overlap); etc. Contains PS00211
                     ABC transporters family signature and PS00017
                     ATP/GTP-binding site motif A (P-loop). BELONGS TO THE
                     ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS)
                     Protein product from Mb1250c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1250c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XXQ1"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR025302"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXQ1"
BEGIN
        1 MSADNHQVPI EIRGLTKHFG SVRALDGLDL TVREGEVHGF LGPNGAGKST TLRILLGLVK
       61 ADGGSVRLLG GDPWTDAVDL HRHIAYVPGD VTLWPSLTGG ETIDLLARMR GGIDNARRAE
      121 LIERFGLDPT KKARTYSKGN RQKVSLISAL SSHATLLLLD EPSSGLDPLM ENVFQQCIGE
      181 ARQRGVTVLL SSHILAETEA LCEKVTIIRA GKTVESGSLD ALRHLSRTSI KAEMIGDPGD
      241 LSRIKGVEDI SIEGTTVRAQ VDSESLRELI QVLGHAGVRS LVSQPPTLEE LFLRHYSLGP
      301 EVAAEQQVAT P
//