LOCUS       SIT99833.1               425 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN protein.
ACCESSION   LT708304-1245
PROTEIN_ID  SIT99833.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1232"
                     /note="Mb1232, -, len: 425 aa. Equivalent to Rv1200, len:
                     425 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 425 aa overlap). Probable conserved
                     integral membrane transport protein, possibly member of
                     major facilitator superfamily (MFS), similar to others
                     e.g. YHJE_ECOLI|P37643 hypothetical metabolite transport
                     protein from Escherichia coli (440 aa), FASTA scores: opt:
                     1047, E(): 0, (39.1% identity in 427 aa overlap); etc.
                     Contains PS00217 Sugar transport proteins signature 2.
                     Protein product from Mb1232 detected using SWATH mass
                     spectrometry. Mb1232 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYL7"
                     /db_xref="InterPro:IPR004736"
                     /db_xref="InterPro:IPR005828"
                     /db_xref="InterPro:IPR005829"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYL7"
BEGIN
        1 MKRVALACLV GSAIEFYDFL IYGTAAALVF PTVFFPHLDP TVAAVASMGT FAVAFLSRPF
       61 GAAVFGYFGD RLGRKKTLVA TLLIMGLATV TVGLVPTTVA IGAAAPLILT TMRLLQGFAV
      121 GGEWAGSALL SAEYAPASKR GWYGMFTVVG GGIALVLTSL TFLGVNYTIG ESSPTFMQWG
      181 WRIPFLVSAA LIAVALYVRF NIDETPVFAR ERADEKTRLG PAETPIAQVL RRQRREIVLA
      241 AGSAVCCFGF VYLASTYLAS YAQTRLGYSR GSILFDSVLG GLLCIVFTAL SSALCDQLGR
      301 RRVLLAGWAV ALPWSLLVMP LIDSGSPSLF AVAVVGMYAI GGFGFGPTAS FIPELFATSY
      361 RYTGSALAAN LAGVAGGALP PVIAGALVAT YGSWAIGVML AILALISLVC TYRLPETAGS
      421 ALVSR
//