LOCUS SIT99833.1 425 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN protein. ACCESSION LT708304-1245 PROTEIN_ID SIT99833.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1232" /note="Mb1232, -, len: 425 aa. Equivalent to Rv1200, len: 425 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 425 aa overlap). Probable conserved integral membrane transport protein, possibly member of major facilitator superfamily (MFS), similar to others e.g. YHJE_ECOLI|P37643 hypothetical metabolite transport protein from Escherichia coli (440 aa), FASTA scores: opt: 1047, E(): 0, (39.1% identity in 427 aa overlap); etc. Contains PS00217 Sugar transport proteins signature 2. Protein product from Mb1232 detected using SWATH mass spectrometry. Mb1232 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XYL7" /db_xref="InterPro:IPR004736" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="UniProtKB/TrEMBL:A0A1R3XYL7" BEGIN 1 MKRVALACLV GSAIEFYDFL IYGTAAALVF PTVFFPHLDP TVAAVASMGT FAVAFLSRPF 61 GAAVFGYFGD RLGRKKTLVA TLLIMGLATV TVGLVPTTVA IGAAAPLILT TMRLLQGFAV 121 GGEWAGSALL SAEYAPASKR GWYGMFTVVG GGIALVLTSL TFLGVNYTIG ESSPTFMQWG 181 WRIPFLVSAA LIAVALYVRF NIDETPVFAR ERADEKTRLG PAETPIAQVL RRQRREIVLA 241 AGSAVCCFGF VYLASTYLAS YAQTRLGYSR GSILFDSVLG GLLCIVFTAL SSALCDQLGR 301 RRVLLAGWAV ALPWSLLVMP LIDSGSPSLF AVAVVGMYAI GGFGFGPTAS FIPELFATSY 361 RYTGSALAAN LAGVAGGALP PVIAGALVAT YGSWAIGVML AILALISLVC TYRLPETAGS 421 ALVSR //