LOCUS       SIT99824.1               304 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Putative
            hydrolase protein.
ACCESSION   LT708304-1236
PROTEIN_ID  SIT99824.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1223"
                     /note="Mb1223, -, len: 304 aa. Equivalent to Rv1191, len:
                     304 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 304 aa overlap). Conserved hypothetical
                     protein, similar to Q54528 RDMC from Streptomyces
                     purpurascens (298 aa), FASTA scores: opt: 196, E():
                     1.5e-05, (27.5% identity in 269 aa overlap);
                     Rv0134|MTCI5.08 (300 aa), FASTA scores: opt: 197, E():
                     6.6e-06, (26.4% identity in 299 aa overlap), some
                     similarity to PIP_NEIGO|P42786 proline iminopeptidase (EC
                     3.4.11.5) (310 aa), FASTA scores: opt: 196, E(): 1.3e-05,
                     (32.2% identity in 152 aa overlap). Contains PS00044
                     Bacterial regulatory proteins, lysR family signature.
                     Protein product from Mb1223 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1223 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR000073"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXN6"
BEGIN
        1 MAVAIARPKL EGNIAVGEDR RIGFAEFGAP QGRAVFWLHG TPGARRQIPT EARVYAEHHN
       61 IRLIGVDRPG IGASTPHQYE TILAFADDLR TIADTLGIDK MAVVGLSGGG PYTLACAAGL
      121 PDRVVAAGVL GGVAPTRGPD AISGGLMRLG SAVAPLLQVG GTPLRLGASL LIRAARPVAS
      181 PALDLYGLLS PRADRHLLAR PEFKAMFLDD LLNGSRKQLA APFADVIAFA RDWGFRLDEV
      241 KVPVRWWHGD HDHIVPFSHG EHVVSRLPDA KLLHLPGESH LAGLGRGEEI LSTLMQIWDR
      301 DLRK
//