LOCUS       SIT99817.1               359 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            EXPORTED PROTEIN protein.
ACCESSION   LT708304-1229
PROTEIN_ID  SIT99817.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1216C"
                     /note="Mb1216c, -, len: 359 aa. Equivalent to Rv1184c,
                     len: 359 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 359 aa overlap). Possible exported
                     protein with potential N-terminal signal sequence. Similar
                     to several Mycobacterial hypothetical proteins e.g.
                     Q49633|U00010) Protein B1170_F3_112 from M. leprae (391
                     aa), FASTA scores: opt: 1422, E(): 0, (62.7% identity in
                     338 aa overlap). Also similar to Rv3822, Rv3539, Rv1430,
                     Rv0151c, etc. Protein product from Mb1216c detected using
                     SWATH mass spectrometry. Mb1216c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR013228"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXL5"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MKRVIAGAFA VWLVGWAGGF GTAIAASEPA YPWAPGPPPS PSPVGDASTA KVVYALGGAR
       61 MPGIPWYEYT NQAGSQYFPN AKHDLIDYPA GAAFSWWPTM LLPPGSHQDN MTVGVAVKDG
      121 TNSLDNAIHH GTDPAAAVGL SQGSLVLDQE QARLANDPTA PAPDKLQFTT FGDPTGRHAF
      181 GASFLARIFP PGSHIPIPFI EYTMPQQVDS QYDTNHVVTA YDGFSDFPDR PDNLLAVANA
      241 AIGAAIAHTP IGFTGPGDVP PQNIRTTVNS RGATTTTYLV PVNHLPLTLP LRYLGMSDAE
      301 VDQIDSVLQP QIDAAYARND NWFTRPVSVD PVRGLDPLTA PGSIVEGARG LLGSPAFGG
//