LOCUS SIT99812.1 362 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE AMINOTRANSFERASE protein. ACCESSION LT708304-1224 PROTEIN_ID SIT99812.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1211" /note="Mb1211, -, len: 362 aa. Equivalent to Rv1178, len: 362 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 362 aa overlap). Probable aminotransferase (EC 2.6.1.-), weak similarity to many aspartate aminotransferases e.g. Q55679|D64000 SLL0006 aspartate aminotransferase from Synechocystis sp. (394 aa), FASTA scores: opt: 218, E(): 1.3e-25, (32.5% identity in 379 aa overlap). Contains PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. Also similar to Mycobacterium tuberculosis aminotransferases Rv2294, Rv0075, etc. Protein product from Mb1211 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1211 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZP9" /db_xref="InterPro:IPR004838" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR019880" /db_xref="UniProtKB/TrEMBL:A0A1R3XZP9" BEGIN 1 MSASLPVFPW DTLADAKALA GAHPDGIVDL SVGTPVDPVA PLIQEALAAA SAAPGYPATA 61 GTARLRESVV AALARRYGIT RLTEAAVLPV IGTKELIAWL PTLLGLGGAD LVVVPELAYP 121 TYDVGARLAG TRVLRADALT QLGPQSPALL YLNSPSNPTG RVLGVDHLRK VVEWARGRGV 181 LVVSDECYLG LGWDAEPVSV LHPSVCDGDH TGLLAVHSLS KSSSLAGYRA GFVVGDLEIV 241 AELLAVRKHA GMMVPAPVQA AMVAALDDDA HERQQRERYA QRRAALLPAL GSAGFAVDYS 301 DAGLYLWATR GEPCRDSVAW LAQRGILVAP GDFYGPGGAQ HVRVALTATD ERVAAAVGRL 361 TC //