LOCUS       SIT99812.1               362 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            AMINOTRANSFERASE protein.
ACCESSION   LT708304-1224
PROTEIN_ID  SIT99812.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1211"
                     /note="Mb1211, -, len: 362 aa. Equivalent to Rv1178, len:
                     362 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 362 aa overlap). Probable
                     aminotransferase (EC 2.6.1.-), weak similarity to many
                     aspartate aminotransferases e.g. Q55679|D64000 SLL0006
                     aspartate aminotransferase from Synechocystis sp. (394
                     aa), FASTA scores: opt: 218, E(): 1.3e-25, (32.5% identity
                     in 379 aa overlap). Contains PS00105 Aminotransferases
                     class-I pyridoxal-phosphate attachment site. Also similar
                     to Mycobacterium tuberculosis aminotransferases Rv2294,
                     Rv0075, etc. Protein product from Mb1211 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb1211 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZP9"
                     /db_xref="InterPro:IPR004838"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="InterPro:IPR019880"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZP9"
BEGIN
        1 MSASLPVFPW DTLADAKALA GAHPDGIVDL SVGTPVDPVA PLIQEALAAA SAAPGYPATA
       61 GTARLRESVV AALARRYGIT RLTEAAVLPV IGTKELIAWL PTLLGLGGAD LVVVPELAYP
      121 TYDVGARLAG TRVLRADALT QLGPQSPALL YLNSPSNPTG RVLGVDHLRK VVEWARGRGV
      181 LVVSDECYLG LGWDAEPVSV LHPSVCDGDH TGLLAVHSLS KSSSLAGYRA GFVVGDLEIV
      241 AELLAVRKHA GMMVPAPVQA AMVAALDDDA HERQQRERYA QRRAALLPAL GSAGFAVDYS
      301 DAGLYLWATR GEPCRDSVAW LAQRGILVAP GDFYGPGGAQ HVRVALTATD ERVAAAVGRL
      361 TC
//