LOCUS SIT99799.1 635 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 probable conserved lipoprotein lpqw protein. ACCESSION LT708304-1211 PROTEIN_ID SIT99799.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lpqW" /locus_tag="BQ2027_MB1198" /note="Mb1198, lpqW, len: 635 aa. Equivalent to Rv1166, len: 635 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 635 aa overlap). Probable Lipoprotein LpqW, almost identical in part to G2384665|AF009358 Mycobacterium tuberculosis gene fragment ORFA2-898 (FRAGMENT) (59 aa) (93.9% identity in 49 aa overlap) (see citation below). Also similar to Rv1280c and Rv2585c. Contains possible N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Protein product from Mb1198 detected using SWATH mass spectrometry. Mb1198 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR000914" /db_xref="InterPro:IPR039424" /db_xref="UniProtKB/TrEMBL:A0A1R3XXK3" BEGIN 1 MGVPSPVRRV CVTVGALVAL ACMVLAGCTV SPPPAPQSTD TPRSTPPPPR RPTQIIMGID 61 WIGPGFNPHL LSDLSPVNAA ISALVLPSAF RPIPDPNTPT GSRWEMDPTL LVSADVTNNH 121 PFTVTYKIRP EAQWTDNAPI AADDFWYLWQ QMVTQPGVVD PAGYHLITSV QSLEGGKQAV 181 VTFAQPYPAW RELFTDILPA HIVKDIPGGF ASGLARALPV TGGQFRVENI DPQRDEILIA 241 RNDRYWGPPS KPGIILFRRA GAPAALADSV RNGDTQVAQV HGGSAAFAQL SAIPDVRTAR 301 IVTPRVMQFT LRANVPKLAD TQVRKAILGL LDVDLLAAVG AGTDNTVTLD QAQIRSPSDP 361 GYVPTAPPAM SSAAALGLLE ASGFQVDTNT SVSPAPSVPD STTTSVSTGP PEVIRGRISK 421 DGEQLTLVIG VAANDPTSVA VANTAADQLR DVGIAATVLA LDPVTLYHDA LNDNRVDAIV 481 GWRQAGGNLA TLLASRYGCP ALQATTVPAA NAPTTAPSAP IGPTPSAAPD TATPPPTAPR 541 RPSDPGALVK APSNLTGICD RSIQSNIDAA LNGTKNINDV ITAVEPRLWN MSTVLPILQD 601 TTIVAAGPSV QNVSLSGAVP VGIVGDAGQW VKTGQ //