LOCUS       SIT99799.1               635 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            conserved lipoprotein lpqw protein.
ACCESSION   LT708304-1211
PROTEIN_ID  SIT99799.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lpqW"
                     /locus_tag="BQ2027_MB1198"
                     /note="Mb1198, lpqW, len: 635 aa. Equivalent to Rv1166,
                     len: 635 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 635 aa overlap). Probable Lipoprotein
                     LpqW, almost identical in part to G2384665|AF009358
                     Mycobacterium tuberculosis gene fragment ORFA2-898
                     (FRAGMENT) (59 aa) (93.9% identity in 49 aa overlap) (see
                     citation below). Also similar to Rv1280c and Rv2585c.
                     Contains possible N-terminal signal sequence and
                     appropriately positioned PS00013 Prokaryotic membrane
                     lipoprotein lipid attachment site. Protein product from
                     Mb1198 detected using SWATH mass spectrometry. Mb1198
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR000914"
                     /db_xref="InterPro:IPR039424"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXK3"
BEGIN
        1 MGVPSPVRRV CVTVGALVAL ACMVLAGCTV SPPPAPQSTD TPRSTPPPPR RPTQIIMGID
       61 WIGPGFNPHL LSDLSPVNAA ISALVLPSAF RPIPDPNTPT GSRWEMDPTL LVSADVTNNH
      121 PFTVTYKIRP EAQWTDNAPI AADDFWYLWQ QMVTQPGVVD PAGYHLITSV QSLEGGKQAV
      181 VTFAQPYPAW RELFTDILPA HIVKDIPGGF ASGLARALPV TGGQFRVENI DPQRDEILIA
      241 RNDRYWGPPS KPGIILFRRA GAPAALADSV RNGDTQVAQV HGGSAAFAQL SAIPDVRTAR
      301 IVTPRVMQFT LRANVPKLAD TQVRKAILGL LDVDLLAAVG AGTDNTVTLD QAQIRSPSDP
      361 GYVPTAPPAM SSAAALGLLE ASGFQVDTNT SVSPAPSVPD STTTSVSTGP PEVIRGRISK
      421 DGEQLTLVIG VAANDPTSVA VANTAADQLR DVGIAATVLA LDPVTLYHDA LNDNRVDAIV
      481 GWRQAGGNLA TLLASRYGCP ALQATTVPAA NAPTTAPSAP IGPTPSAAPD TATPPPTAPR
      541 RPSDPGALVK APSNLTGICD RSIQSNIDAA LNGTKNINDV ITAVEPRLWN MSTVLPILQD
      601 TTIVAAGPSV QNVSLSGAVP VGIVGDAGQW VKTGQ
//