LOCUS       SIT99798.1               628 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            GTP-BINDING TRANSLATION ELONGATION FACTOR TYPA (TYROSINE
            PHOSPHORYLATED PROTEIN A) (GTP-BINDING PROTEIN) protein.
ACCESSION   LT708304-1210
PROTEIN_ID  SIT99798.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="typA"
                     /locus_tag="BQ2027_MB1197"
                     /note="Mb1197, typA, len: 628 aa. Equivalent to Rv1165,
                     len: 628 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 628 aa overlap). Possible typA
                     (alternate gene name: bipA), GTP-binding translation
                     elongation factor, similar to several e.g.
                     P32132|TYPA_ECOLI|BIPA|B387 Escherichia coli (591 aa);
                     YIHK_SYNY3|P72749 GTP-binding protein TYPA/BIPA homolog
                     from synechocystis sp. (597 aa), FASTA scores: E(): 0,
                     (46.9% identity in 610 aa overlap); and to elongation
                     factor EF-G from many organims e.g. EFG_MICLU|P09952
                     micrococcus luteus (701 aa), FASTA scores: E(): 3e-24,
                     (29.8% identity in 500 aa overlap). BELONGS TO THE
                     GTP-BINDING ELONGATION FACTOR FAMILY, TYPA SUBFAMILY.
                     Protein product from Mb1197 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1197 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XXJ4"
                     /db_xref="InterPro:IPR000640"
                     /db_xref="InterPro:IPR000795"
                     /db_xref="InterPro:IPR004161"
                     /db_xref="InterPro:IPR005225"
                     /db_xref="InterPro:IPR006298"
                     /db_xref="InterPro:IPR009000"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR035647"
                     /db_xref="InterPro:IPR035651"
                     /db_xref="InterPro:IPR042116"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXJ4"
BEGIN
        1 MPFRNVAIVA HVDHGKTTLV DAMLRQSGAL RERGELQERV MDTGDLEREK GITILAKNTA
       61 VHRHHPDGTV TVINVIDTPG HADFGGEVER GLSMVDGVLL LVDASEGPLP QTRFVLRKAL
      121 AAHLPVILVV NKTDRPDARI AEVVDASHDL LLDVASDLDD EAAAAAEHAL GLPTLYASGR
      181 AGVASTTAPP DGQVPDGTNL DPLFEVLEKH VPPPKGEPDA PLQALVTNLD ASTFLGRLAL
      241 IRIYNGRIRK GQQVAWIRQV DGQQTVTTAK ITELLATEGV ERKPTDAAVA GDIVAVAGLP
      301 EIMIGDTLAA SANPVALPRI TVDEPAISVT IGTNTSPLAG KVGGHKLTAR MVRSRLDAEL
      361 VGNVSIRVVD IGAPDAWEVQ GRGELALAVL VEQMRREGFE LTVGKPQVVT KTIDGTLHEP
      421 FESMTVDCPE EYIGAVTQLM AARKGRMVEM ANHTTGWVRM DFVVPSRGLI GWRTDFLTET
      481 RGSGVGHAVF DGYRPWAGEI RARHTGSLVS DRAGAITPFA LLQLADRGQF FVEPGQQTYE
      541 GMVVGINPRP EDLDINVTRE KKLTNMRSST ADVIETLAKP LQLDLERAME LCAPDECVEV
      601 TPEIVRIRKV ELAAAARARS RARTKARG
//