LOCUS       SIT99796.1               201 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            RESPIRATORY NITRATE REDUCTASE (DELTA CHAIN) NARJ protein.
ACCESSION   LT708304-1208
PROTEIN_ID  SIT99796.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="narJ"
                     /locus_tag="BQ2027_MB1195"
                     /note="Mb1195, narJ, len: 201 aa. Equivalent to Rv1163,
                     len: 201 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 201 aa overlap). Probable narJ,
                     respiratory nitrate reductase delta chain (EC 1.7.99.4).
                     Similar to others e.g. P42178|NARJ_BACSU NITRATE REDUCTASE
                     DELTA CHAIN from Bacillus subtilis (184 aa), FASTA scores:
                     opt: 254, E(): 1.9e-10, (31.8% identity in 179 aa
                     overlap); etc. Strong similarity to region from aa 260
                     -410 of Rv1736c|MTCY04C12.21c|NARX PROBABLE NITRATE
                     REDUCTASE from Mycobacterium tuberculosis (64.8% identity
                     in 159 aa overlap). Protein product from Mb1195 detected
                     using SWATH mass spectrometry. Mb1195 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XXJ7"
                     /db_xref="InterPro:IPR003765"
                     /db_xref="InterPro:IPR020945"
                     /db_xref="InterPro:IPR036411"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXJ7"
BEGIN
        1 MWQSASLLLA YPDDGLAERL HMVDALRAHQ TGPAAALLGR TVAELRALAP MAAAAQYVET
       61 FDMRRRSTMY LTYWTAGDTR NRGREMLAFA TAYRDAGVKP PRTEAPDYLP VVLEFAATVD
      121 PEAGRRLLTE HRVPIDVLRG ALADAKSPYE YTVAAICETL PAATNQEVRR AQRLAQSGPP
      181 AEAVGLQPFT LTVPPKRAEG A
//