LOCUS       SIT99793.1               141 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            MUTATOR PROTEIN MUTT2 (7,8-dihydro-8-oxoguanine-triphosphatase)
            (8-OXO-DGTPASE) protein.
ACCESSION   LT708304-1205
PROTEIN_ID  SIT99793.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mutT2"
                     /locus_tag="BQ2027_MB1192"
                     /note="Mb1192, mutT2, len: 141 aa. Equivalent to Rv1160,
                     len: 141 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 141 aa overlap). Probable mutT, mutator
                     protein or homolog (EC 3.6.1.-). More similar to
                     D908197|g1742860 MutT homolog from Escherichia coli (135
                     aa), FASTA scores: opt: 226, E():1.1e-08, (39.7% identity
                     in 116 aa overlap); than to MUTT_ECOLI|P08337 MUTATOR MUTT
                     PROTEIN from Escherichia coli (129 aa), FASTA scores: opt:
                     180, E(): 1.2e-05, (27.1% identity in 129 aa overlap).
                     Contains PS00893 mutT domain signature. Protein product
                     from Mb1192 detected using SWATH mass spectrometry. Mb1192
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYH8"
                     /db_xref="InterPro:IPR000086"
                     /db_xref="InterPro:IPR015797"
                     /db_xref="InterPro:IPR020084"
                     /db_xref="InterPro:IPR020476"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYH8"
BEGIN
        1 MLNQIVVAGA IVRGCTVLVA QRVRPPELAG RWELPGGKVA AGETERAALA RELAEELGLE
       61 VADLAVGDRV GDDIALNGTT TLRAYRVHLL GGEPRARDHR ALCWVTAAEL HDVDWVPADR
      121 GWIADLARTL NGSAADVHRR C
//