LOCUS SIT99790.1 227 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Conserved alanine and proline rich protein protein. ACCESSION LT708304-1202 PROTEIN_ID SIT99790.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1189C" /note="Mb1189c, -, len: 227 aa. Equivalent to Rv1158c, len: 227 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 227 aa overlap). Conserved hypothetical Ala-, Pro-rich protein, similar to other proline rich proteins and extensins e.g. MMSAP62|g633250 house mouse (485 aa), FASTA scores: opt: 367, E(): 1.2e-08, (36.3% identity in 212 aa overlap). Has hydrophobic stretch at N-terminus suggestive of secretion signal. Mb1189c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="UniProtKB/TrEMBL:A0A1R3XXI3" BEGIN 1 MPTIWTFVRA AAVLVGSSAA LLTGGIAHAD PAPAPAPAPN IPQQLISSAA NAPQILQNLA 61 TALGATPPLS APKVAEPAPA APGITATFPG LTPAAPAAAA APALTPSIPG VNAPIPGITP 121 AAPALPVTAP AAAPTIPGVN APIPGITAPA PAAAAVPASV PGVPSAKVDL PQLPYLPLQV 181 PQQLSLPADL PALASGVIPA APIAPTPPAP GAPALPPGPP SLLAALP //