LOCUS       SIT99790.1               227 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Conserved
            alanine and proline rich protein protein.
ACCESSION   LT708304-1202
PROTEIN_ID  SIT99790.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1189C"
                     /note="Mb1189c, -, len: 227 aa. Equivalent to Rv1158c,
                     len: 227 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 227 aa overlap). Conserved hypothetical
                     Ala-, Pro-rich protein, similar to other proline rich
                     proteins and extensins e.g. MMSAP62|g633250 house mouse
                     (485 aa), FASTA scores: opt: 367, E(): 1.2e-08, (36.3%
                     identity in 212 aa overlap). Has hydrophobic stretch at
                     N-terminus suggestive of secretion signal. Mb1189c found
                     to be expressed during exponential growth in Sauton's
                     minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXI3"
BEGIN
        1 MPTIWTFVRA AAVLVGSSAA LLTGGIAHAD PAPAPAPAPN IPQQLISSAA NAPQILQNLA
       61 TALGATPPLS APKVAEPAPA APGITATFPG LTPAAPAAAA APALTPSIPG VNAPIPGITP
      121 AAPALPVTAP AAAPTIPGVN APIPGITAPA PAAAAVPASV PGVPSAKVDL PQLPYLPLQV
      181 PQQLSLPADL PALASGVIPA APIAPTPPAP GAPALPPGPP SLLAALP
//