LOCUS SIT99778.1 216 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 SAM- dependent methyltransferase protein. ACCESSION LT708304-1190 PROTEIN_ID SIT99778.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1178" /note="Mb1178, -, len: 216 aa. Equivalent to Rv1147, len: 216 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 216 aa overlap). Conserved hypothetical protein, similar to many conserved hypothetical proteins, and some similarity to several methyltransferases e.g. Q05197|PMTA_RHOSH phosphatidylethanolamine N-methyltransferase (EC 2.1.1.17) from R. sphaeroides (203 aa), FASTA scores: opt: 156, E(): 0.00073, (27.6% identity in 156 aa overlap). Protein product from Mb1178 detected using SWATH mass spectrometry. Mb1178 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR029063" /db_xref="UniProtKB/TrEMBL:A0A1R3XXH3" BEGIN 1 MTSGAAASAS RVDHPLFARI WPVVAAHEAE AIRALRRENL AGLSGRVLEV GAGVGTNFAY 61 YPVAVEQVIA MEPEPRLAAK ARIAAADAPV PIVVTDKTVE EFRDTETFDA VVCSLVLCSV 121 SDPGAVLAHL RSLLRRGGEL RYLEHVASAG ARGRVQRFVD ATFWPRLAGN CHTHRHTERA 181 ILDAGFVVDS SRREWAFPAW VPLPVSELAL GRAHRT //