LOCUS       SIT99778.1               216 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 SAM-
            dependent methyltransferase protein.
ACCESSION   LT708304-1190
PROTEIN_ID  SIT99778.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1178"
                     /note="Mb1178, -, len: 216 aa. Equivalent to Rv1147, len:
                     216 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 216 aa overlap). Conserved hypothetical
                     protein, similar to many conserved hypothetical proteins,
                     and some similarity to several methyltransferases e.g.
                     Q05197|PMTA_RHOSH phosphatidylethanolamine
                     N-methyltransferase (EC 2.1.1.17) from R. sphaeroides (203
                     aa), FASTA scores: opt: 156, E(): 0.00073, (27.6% identity
                     in 156 aa overlap). Protein product from Mb1178 detected
                     using SWATH mass spectrometry. Mb1178 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXH3"
BEGIN
        1 MTSGAAASAS RVDHPLFARI WPVVAAHEAE AIRALRRENL AGLSGRVLEV GAGVGTNFAY
       61 YPVAVEQVIA MEPEPRLAAK ARIAAADAPV PIVVTDKTVE EFRDTETFDA VVCSLVLCSV
      121 SDPGAVLAHL RSLLRRGGEL RYLEHVASAG ARGRVQRFVD ATFWPRLAGN CHTHRHTERA
      181 ILDAGFVVDS SRREWAFPAW VPLPVSELAL GRAHRT
//