LOCUS SIT99763.1 576 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED MEMBRANE PROTEIN protein. ACCESSION LT708304-1175 PROTEIN_ID SIT99763.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1163" /note="Mb1163, -, len: 576 aa. Equivalent to Rv1132, len: 576 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 576 aa overlap). Conserved membrane protein, similar to O06827|Rv1431|MTCY493.23C membrane protein from Mycobacterium tuberculosis (589 aa), fasta scores: opt: 1811, E(): 0, (48.2% identity in 585 aa overlap). Protein product from Mb1163 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1163 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XYE9" /db_xref="InterPro:IPR021941" /db_xref="UniProtKB/TrEMBL:A0A1R3XYE9" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MGFLQPRLPD IDLAEWSQGS RSQKIRPMAQ HWAEVGFGTP VLLHLFYVAK ILLYVLVGWL 61 IVLTTKGIDG FTDAAAWYAE PIVFEKVVLY TMLFEVIGLG CGFGPLNNRF FPPMGSILYW 121 MRFGTIRLPP WPDRVPWTRG TKRKPVDVAL YALLVMMLLS ALFTDGAGPI PELGTMVGLL 181 PAWQIVLILL LLGVLGLRDK VIFLAARGEV YATLTVTFLF GRLNGIDMIV AAKLVFLVIW 241 IGAATSKLNR HFPFVISTMM SNNPLFRPRF IKRMFFKKFP GDLRPGLLSR IVAHVSTVIE 301 MCVPVVLFVA HGGWPTVVAA TIMVCFHLGI LTAIPMGVPL EWNVFMIFGV LSLFVGHACL 361 GLADVKNPVP LAILIAVVAG IVIAGNVFPR KISFLAAMRY YAGNWDTTLW CIKPSAEDKI 421 NRGIVAIASM PAAQLERFYG KDRAQIPMYL GYAFRAMNSH GRALFTLAHR AMAGHDEDDY 481 VITDGERVCS TAVGWNFGDG HLHNEQLIAA MQQRCGFQPG EVRVVLLDAQ PIHRQTQEYR 541 LVDAATGEFE RGYVRVADMV NRQPWDDDVP VHVLPG //