LOCUS SIT99760.1 486 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSCRIPTIONAL REGULATOR PROTEIN protein. ACCESSION LT708304-1172 PROTEIN_ID SIT99760.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1160C" /note="Mb1160c, -, len: 486 aa. Equivalent to Rv1129c, len: 486 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 486 aa overlap). Possible transcriptional regulator protein, similar to Rv0465c|MTV038.09c Mycobacterium tuberculosis (474 aa), FASTA scores: E(): 0, (47.4% identity in 468 aa overlap). Helix turn helix motif present from aa 32-53. Protein product from Mb1160c detected using SWATH mass spectrometry." /db_xref="GOA:A0A1R3XXF4" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010359" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR018653" /db_xref="InterPro:IPR026281" /db_xref="UniProtKB/TrEMBL:A0A1R3XXF4" BEGIN 1 MTRSNVLPVA RTYSRTFSGA RLRRLRQERG LTQVALAKAL DLSTSYVNQL ENDQRPITVP 61 VLLLLTERFD LSAQYFSSDS DARLVADLSD VFTDIGVEHA VSGAQIEEFV ARMPEVGHSL 121 VAVHRRLRAA TEELEGYRSR ATAETELPPA RPMPFEEVRD FFYDRNNYIH DLDMAAERMF 181 TESGMRTGGL DIQLAELMRD RFGISVVIDD NLPDTAKRRY HPDTKVLRVA HWLMPGQRAF 241 QIATQLALVG QSDLISSIVA TDDQLSTEAR GVARIGLANY FAGAFLLPYR EFHRAAEQLR 301 YDIDLLGRRF GVGFETVCHR LSTLQRPRQR GIPFIFVRTD KAGNISKRQS ATAFHFSRVG 361 GSCPLWVVHD AFAQPERIVR QVAQMPDGRS YFWVAKTTAA DGLGYLGPHK NFAVGLGCDL 421 AHAHKLVYST GVVLDDPSTE VPIGAGCKIC NRTSCAQRAF PYLGGRVAVD ENAGSSLPYS 481 STEQSV //