LOCUS       SIT99741.1               327 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Rhomboid
            family protein protein.
ACCESSION   LT708304-1153
PROTEIN_ID  SIT99741.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1141C"
                     /note="Mb1141c, -, len: 327 aa. Equivalent to Rv1111c,
                     len: 327 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 327 aa overlap). Conserved hypothetical
                     protein, N-terminal domain is hydrophobic, C-terminal half
                     is very rich in Arg. Equivalent to AL049491|MLCB1222_2
                     hypothetical protein from Mycobacterium leprae (379 aa)
                     (46.0% identity in 374 aa overlap). Start changed since
                     first submission. Protein product from Mb1141c detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb1141c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XXE0"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXE0"
BEGIN
        1 MSAQRARSAV QASHRSIHPH IPGVPWWAAI LIAVTATAIG YAIDAGSGHK ALTLVFTGCY
       61 IAGCVGAVLA VRQSDLFTAL VQPPLILFCA VPGAYWLFHG GTIGKFKDLL INCGYSLIER
      121 FPLMLGTAAG VLLIGLVRWY LGTALFDSIA RKLSSLMTGD SDDDGGRRSA QRPARTRSRH
      181 ARPPSEDNRE PIAERRSRRR PRPQNDPHPR RNAHERPAPR SSRFDSYRSY QPSEPSGPAE
      241 PVNRYERRGA RYQPYARYEP TYEPQRRRAR PSEPTNPTHH PISQVRYRGS ATRDARRDNY
      301 REEQRFDRRD RSRAPRRPPA ESWEYDV
//