LOCUS SIT99737.1 85 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable exodeoxyribonuclease VII (small subunit) xseB (Exonuclease VII small subunit) protein. ACCESSION LT708304-1149 PROTEIN_ID SIT99737.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="xseB" /locus_tag="BQ2027_MB1137C" /note="Mb1137c, xseB, len: 85 aa. Equivalent to Rv1107c, len: 85 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 85 aa overlap). Probable xseB, exonuclease VII small subunit (EC 3.1.11.6). Equivalent to AL049491|MLCB1222_6 Mycobacterium leprae (87 aa) (77.9% identity in 68 aa overlap). Similar to P43914|EX7S_HAEIN EXODEOXYRIBONUCLEASE SMALL SUBUNIT from H. influenzae (84 aa), FASTA scores: opt: 126, E(): 0.006, (37.3% identity in 67 aa overlap); and P22938|EX7S_ECOLI EXODEOXYRIBONUCLEASE SMALL SUBUNIT from Escherichia coli (79 aa), FASTA scores: opt: 125, E(): 0.0067, (39.7% identity in 58 aa overlap). BELONGS TO THE XSEB FAMILY. Protein product from Mb1137c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1137c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P67457" /db_xref="InterPro:IPR003761" /db_xref="InterPro:IPR037004" /db_xref="UniProtKB/Swiss-Prot:P67457" BEGIN 1 MVCDPNGDDT GRTHATVPVS QLGYEACRDE LMEVVRLLEQ GGLDLDASLR LWERGEQLAK 61 RCEEHLAGAR QRVSDVLAGD EAQNG //