LOCUS       SIT99737.1                85 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            exodeoxyribonuclease VII (small subunit) xseB (Exonuclease
            VII small subunit) protein.
ACCESSION   LT708304-1149
PROTEIN_ID  SIT99737.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="xseB"
                     /locus_tag="BQ2027_MB1137C"
                     /note="Mb1137c, xseB, len: 85 aa. Equivalent to Rv1107c,
                     len: 85 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 85 aa overlap). Probable xseB,
                     exonuclease VII small subunit (EC 3.1.11.6). Equivalent to
                     AL049491|MLCB1222_6 Mycobacterium leprae (87 aa) (77.9%
                     identity in 68 aa overlap). Similar to P43914|EX7S_HAEIN
                     EXODEOXYRIBONUCLEASE SMALL SUBUNIT from H. influenzae (84
                     aa), FASTA scores: opt: 126, E(): 0.006, (37.3% identity
                     in 67 aa overlap); and P22938|EX7S_ECOLI
                     EXODEOXYRIBONUCLEASE SMALL SUBUNIT from Escherichia coli
                     (79 aa), FASTA scores: opt: 125, E(): 0.0067, (39.7%
                     identity in 58 aa overlap). BELONGS TO THE XSEB FAMILY.
                     Protein product from Mb1137c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1137c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P67457"
                     /db_xref="InterPro:IPR003761"
                     /db_xref="InterPro:IPR037004"
                     /db_xref="UniProtKB/Swiss-Prot:P67457"
BEGIN
        1 MVCDPNGDDT GRTHATVPVS QLGYEACRDE LMEVVRLLEQ GGLDLDASLR LWERGEQLAK
       61 RCEEHLAGAR QRVSDVLAGD EAQNG
//