LOCUS       SIT99706.1               240 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            Proline-rich antigen homolog pra protein.
ACCESSION   LT708304-1118
PROTEIN_ID  SIT99706.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pra"
                     /locus_tag="BQ2027_MB1107"
                     /note="Mb1107, pra, len: 240 aa. Equivalent to Rv1078,
                     len: 240 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 240 aa overlap). Probable pra,
                     Proline-rich antigen homolog, equivalent to
                     X65546|MLPRAG_1 proline rich antigen from Mycobacterium
                     leprae (249 aa), FASTA scores: opt: 1162, E(): 3.3e-30,
                     (64.8% identity in 253 aa overlap). Has potential
                     hydrophobic domains. Protein product from Mb1107 detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb1107 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XXA6"
                     /db_xref="InterPro:IPR010432"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXA6"
BEGIN
        1 MTEQPPPGGS YPPPPPPPGP SGGHEPPPAA PPGGSGYAPP PPPSSGSGYP PPPPPPGGGA
       61 YPPPPPSAGG YAPPPPGPAI RTMPTESYTP WITRVLAAFI DWAPYVVLVG IGWVIMLVTQ
      121 TSSCVTSISE YDVGQFCVSQ PSMIGQLVQW LLSVGGLAYL VWNYGYRQGT TGSSIGKSVL
      181 KFKVVSETTG QPIGFGMSVV RQLAHFIDAI ICFVGFLFPL WDAKRQTLAD KIMTTVCVPI
//