LOCUS SIT99706.1 240 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable Proline-rich antigen homolog pra protein. ACCESSION LT708304-1118 PROTEIN_ID SIT99706.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="pra" /locus_tag="BQ2027_MB1107" /note="Mb1107, pra, len: 240 aa. Equivalent to Rv1078, len: 240 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 240 aa overlap). Probable pra, Proline-rich antigen homolog, equivalent to X65546|MLPRAG_1 proline rich antigen from Mycobacterium leprae (249 aa), FASTA scores: opt: 1162, E(): 3.3e-30, (64.8% identity in 253 aa overlap). Has potential hydrophobic domains. Protein product from Mb1107 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1107 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XXA6" /db_xref="InterPro:IPR010432" /db_xref="UniProtKB/TrEMBL:A0A1R3XXA6" BEGIN 1 MTEQPPPGGS YPPPPPPPGP SGGHEPPPAA PPGGSGYAPP PPPSSGSGYP PPPPPPGGGA 61 YPPPPPSAGG YAPPPPGPAI RTMPTESYTP WITRVLAAFI DWAPYVVLVG IGWVIMLVTQ 121 TSSCVTSISE YDVGQFCVSQ PSMIGQLVQW LLSVGGLAYL VWNYGYRQGT TGSSIGKSVL 181 KFKVVSETTG QPIGFGMSVV RQLAHFIDAI ICFVGFLFPL WDAKRQTLAD KIMTTVCVPI //