LOCUS       SIT99700.1               278 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-1112
PROTEIN_ID  SIT99700.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1101"
                     /note="Mb1101, -, len: 278 aa. Equivalent to Rv1072, len:
                     278 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 278 aa overlap). Probable conserved
                     transmembrane protein, equivalent to
                     O07139|B1306.07|Y13803 Protein B1306.07 from Mycobacterium
                     leprae (220 aa), FASTA scores: opt:1032, E(): 0, (75.0%
                     identity in 220 aa overlap); and at the C-terminal end to
                     Q50056|U1740D Mycobacterium leprae (96 aa), FASTA scores:
                     opt: 381, E(): 1.2e-18, (71.6% identity in 81 aa overlap).
                     Similar to Q54192|M80628|STMBLDA_1 TRANSFER RNA-LEU (BLDA)
                     GENE AND ORF from Streptomyces griseus (293 aa), FASTA
                     scores: opt:558, E(): 4.7e-30, (41.5% identity in 299 aa
                     overlap). TBparse score is 0.896. Protein product from
                     Mb1101 detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb1101 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XX96"
                     /db_xref="InterPro:IPR010539"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XX96"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MRETSNPVFR SLPKQRGGYA QFGTGTAQQG FPADPYLAPY REAKATRPLT IDDVVTKTGL
       61 TLAMLAGTAV VSYFLVASNV ALAMPLTLVG ALGGLALVLV ATFGRKQDNP AIVLSYAALE
      121 GLFLGAISFV LANFTVASAN AGVLIGEAIL GTMGVFFGML VVYKTGAIRV TPKFTRMVVA
      181 ALFGVLVLML GNLVLAMFNV GGGEGLGLRS PGPLGIIFSL VCIGIAAFSF LIDFDAADQM
      241 IRAGAPEKAA WGVALGLTVT LVWLYIEILR LLSYLQNE
//