LOCUS SIT99700.1 278 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN protein. ACCESSION LT708304-1112 PROTEIN_ID SIT99700.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1101" /note="Mb1101, -, len: 278 aa. Equivalent to Rv1072, len: 278 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 278 aa overlap). Probable conserved transmembrane protein, equivalent to O07139|B1306.07|Y13803 Protein B1306.07 from Mycobacterium leprae (220 aa), FASTA scores: opt:1032, E(): 0, (75.0% identity in 220 aa overlap); and at the C-terminal end to Q50056|U1740D Mycobacterium leprae (96 aa), FASTA scores: opt: 381, E(): 1.2e-18, (71.6% identity in 81 aa overlap). Similar to Q54192|M80628|STMBLDA_1 TRANSFER RNA-LEU (BLDA) GENE AND ORF from Streptomyces griseus (293 aa), FASTA scores: opt:558, E(): 4.7e-30, (41.5% identity in 299 aa overlap). TBparse score is 0.896. Protein product from Mb1101 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1101 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XX96" /db_xref="InterPro:IPR010539" /db_xref="UniProtKB/TrEMBL:A0A1R3XX96" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MRETSNPVFR SLPKQRGGYA QFGTGTAQQG FPADPYLAPY REAKATRPLT IDDVVTKTGL 61 TLAMLAGTAV VSYFLVASNV ALAMPLTLVG ALGGLALVLV ATFGRKQDNP AIVLSYAALE 121 GLFLGAISFV LANFTVASAN AGVLIGEAIL GTMGVFFGML VVYKTGAIRV TPKFTRMVVA 181 ALFGVLVLML GNLVLAMFNV GGGEGLGLRS PGPLGIIFSL VCIGIAAFSF LIDFDAADQM 241 IRAGAPEKAA WGVALGLTVT LVWLYIEILR LLSYLQNE //