LOCUS       SIT99684.1               254 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 conserved
            protein protein.
ACCESSION   LT708304-1096
PROTEIN_ID  SIT99684.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1085"
                     /note="Mb1085, -, len: 254 aa. Equivalent to Rv1056, len:
                     254 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 254 aa overlap). Conserved hypothetical
                     protein, some similarity in C-terminal region of
                     Rv0140|MTCI5.14|Z92770 Mycobacterium tuberculosis (126
                     aa), FASTA scores: opt: 254, E(): 1.2e-10, (43.4% identity
                     in 106 aa overlap); and to Rv1670. C-terminal region is
                     similar to AL035569|SC8D9.02 hypothetical protein from
                     Streptomyces coelicolor (113 aa), FASTA scores: opt: 282,
                     E(): 4.5e-12, (48.0% identity in 100 aa overlap). Protein
                     product from Mb1085 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1085 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR007361"
                     /db_xref="InterPro:IPR038694"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XX99"
BEGIN
        1 MSVDYPQMAA TRGRIEPAPR RVRGYLGHVL VFDTSAARYV WEVPYYPQYY IPLADVRMEF
       61 LRDENHPQRV QLGPSRLHSL VSAGQTHRSA ARVFDVDGDS PVAGTVRFNW DPLRWFEEDE
      121 PIYGHPRNPY QRADALRSHR HVRVELDGIV LADTRSPVLL FETGIPTRYY IDPADIAFEH
      181 LEPTSTQTLC PYKGTTSGYW SVRVGDAVHR DLAWTYHYPL PAVAPIAGLV AFYNEKVDLT
      241 VDGVALPRPH TQFS
//