LOCUS SIT99684.1 254 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved protein protein. ACCESSION LT708304-1096 PROTEIN_ID SIT99684.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1085" /note="Mb1085, -, len: 254 aa. Equivalent to Rv1056, len: 254 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 254 aa overlap). Conserved hypothetical protein, some similarity in C-terminal region of Rv0140|MTCI5.14|Z92770 Mycobacterium tuberculosis (126 aa), FASTA scores: opt: 254, E(): 1.2e-10, (43.4% identity in 106 aa overlap); and to Rv1670. C-terminal region is similar to AL035569|SC8D9.02 hypothetical protein from Streptomyces coelicolor (113 aa), FASTA scores: opt: 282, E(): 4.5e-12, (48.0% identity in 100 aa overlap). Protein product from Mb1085 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1085 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR007361" /db_xref="InterPro:IPR038694" /db_xref="UniProtKB/TrEMBL:A0A1R3XX99" BEGIN 1 MSVDYPQMAA TRGRIEPAPR RVRGYLGHVL VFDTSAARYV WEVPYYPQYY IPLADVRMEF 61 LRDENHPQRV QLGPSRLHSL VSAGQTHRSA ARVFDVDGDS PVAGTVRFNW DPLRWFEEDE 121 PIYGHPRNPY QRADALRSHR HVRVELDGIV LADTRSPVLL FETGIPTRYY IDPADIAFEH 181 LEPTSTQTLC PYKGTTSGYW SVRVGDAVHR DLAWTYHYPL PAVAPIAGLV AFYNEKVDLT 241 VDGVALPRPH TQFS //