LOCUS SIT99658.1 709 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable Potassium-transporting P-type ATPase B chain KDPB (Potassium- translocating ATPase B chain) (ATP phosphohydrolase [potassium- transporting] B chain) (Potassium binding and translocating subunit B) protein. ACCESSION LT708304-1070 PROTEIN_ID SIT99658.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="kdpB" /locus_tag="BQ2027_MB1059" /note="Mb1059, kdpB, len: 709 aa. Equivalent to Rv1030, len: 709 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 709 aa overlap). Probable kdpB, potassium-transporting P-type ATPase B chain (transmembrane protein) (EC 3.6.3.12), similar to others e.g. ATKB_ECOLI|P03960 potassium-transporting ATPase B chain from Escherichia coli strain K12 (682 aa), FASTA scores: opt: 1481, E(): 0, (63.4% identity in 686 aa overlap); etc. Very similar to AL078610|SCH35.47 H+/K+-exchanging ATPase (EC 3.6.1.36) chain B from Streptomyces coelicolor (707 aa), FASTA scores: opt: 2731, E(): 0, (71.6% identity in 676 aa overlap). Contains PS00154 E1-E2 ATPases phosphorylation site. Protein product from Mb1059 detected using shotgun mass spectrometry." /db_xref="GOA:P63682" /db_xref="InterPro:IPR001757" /db_xref="InterPro:IPR006391" /db_xref="InterPro:IPR008250" /db_xref="InterPro:IPR018303" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR023298" /db_xref="InterPro:IPR023299" /db_xref="InterPro:IPR036412" /db_xref="UniProtKB/Swiss-Prot:P63682" BEGIN 1 MMIARMETSA TAAAATSAPR LRLAKRSLFD PMIVRSALPQ SLRKLAPRVQ ARNPVMLVVL 61 VGAVITTLAF LRDLASSTAQ ENVFNGLVAA FLWFTVLFAN FAEAMAEGRG KAQAAALRKV 121 RSETMANRRT AAGNIESVPS SRLDLDDVVE VSAGETIPSD GEIIEGIASV DESAITGESA 181 PVIRESGGDR SAVTGGTVVL SDRIVVRITA KQGQTFIDRM IALVEGAARQ QTPNEIALNI 241 LLAGLTIIFL LAVVTLQPFA IYSGGGQRVV VLVALLVCLI PTTIGALLSA IGIAGMDRLV 301 QHNVLATSGR AVEAAGDVNT LLLDKTGTIT LGNRQATEFV PINGVSAEAV ADAAQLSSLA 361 DETPEGRSIV VLAKDEFGLR ARDEGVMSHA RFVPFTAETR MSGVDLAEVS GIRRIRKGAA 421 AAVMKWVRDH GGHPTEEVGA IVDGISSGGG TPLVVAEWTD NSSARAIGVV HLKDIVKVGI 481 RERFDEMRRM SIRTVMITGD NPATAKAIAQ EAGVDDFLAE ATPEDKLALI KREQQGGRLV 541 AMTGDGTNDA PALAQADVGV AMNTGTQAAR EAGNMVDLDS DPTKLIEVVE IGKQLLITRG 601 ALTTFSIAND VAKYFAIIPA MFVGLYPVLD KLNVMALHSP RSAILSAVIF NALVIVALIP 661 LALRGVRFRA ESASAMLRRN LLIYGLGGLV VPFIGIKLVD LVIVALGVS //