LOCUS SIT99653.1 319 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Exopolyphosphatas e (EC protein. ACCESSION LT708304-1065 PROTEIN_ID SIT99653.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="ppx2" /locus_tag="BQ2027_MB1054" /EC_number="3.6.1.11" /note="Mb1054, -, len: 319 aa. Equivalent to Rv1026, len: 319 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 319 aa overlap). Conserved hypothetical protein. Equivalent to AL023514|MLCB4.02 hypothetical protein from Mycobacterium leprae (317 aa) (77.9% identity in 321 aa overlap). Similar to GPPA_ECOLI|P25552 guanosine-5'-triphosphate, 3'-diphosphate pyrophoshatase from Escherichia coli (494 aa), FASTA scores: opt: 281, E(): 3.2e-11, (30.6% identity in 291 aa overlap). Protein product from Mb1054 detected using SWATH mass spectrometry. Mb1054 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR003695" /db_xref="UniProtKB/TrEMBL:A0A1R3XY40" BEGIN 1 MALTRVAAID CGTNSIRLLI ADVGAGLARG ELHDVHRETR IVRLGQGVDA TGRFAPEAIA 61 RTRTALTDYA ELLTFHHAER VRMVATSAAR DVVNRDVFFA MTADVLGAAL PGSAAEVITG 121 AEEAELSFRG AVGELGSAGA PFVVVDLGGG STEIVLGEHE VVASYSADIG CVRLTERCLH 181 SDPPTLQEVS TARRLVRERL EPALRTVPLE LARTWVGLAG TMTTLSALAQ SMTAYDAAAI 241 HLSRVPGADL LEVCQRLIGM TRKQRAALAP MHPGRADVIG GGAIVVEELA RELRERAGID 301 QLTVSEHDIL DGIALSLAG //