LOCUS       SIT99648.1               325 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Nucleoside
            triphosphate pyrophosphohydrolase MazG (EC protein.
ACCESSION   LT708304-1060
PROTEIN_ID  SIT99648.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mazG"
                     /locus_tag="BQ2027_MB1049"
                     /EC_number="3.6.1.8"
                     /note="Mb1049, -, len: 325 aa. Equivalent to Rv1021, len:
                     325 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 325 aa overlap). Conserved hypothetical
                     protein, similar to YBL1_STRCI|P33653 hypothetical 26.1 kd
                     protein from Streptomyces cacaoi (242 aa), FASTA scores:
                     opt: 493, E(): 1.1e-23, (42.9% identity in 238 aa
                     overlap). Protein product from Mb1049 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb1049 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="InterPro:IPR004518"
                     /db_xref="InterPro:IPR011551"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XX33"
BEGIN
        1 MIVVLVDPRR PTLVPVEAIE FLRGEVQYTE EMPVAVPWSL PAARSAHAGN DAPVLLSSDP
       61 NHPAVITRLA AGARLISAPD SQRGERLVDA VAMMDKLRTA GPWESEQTHD SLRRYLLEET
      121 YELLDAVRSG SVDQLREELG DLLLQVLFHA RIAEDASQSP FTIDDVADTL MRKLGNRAPG
      181 VLAGESISLE DQLAQWEAAK ASEKARKSVA DDVHTGQPAL ALAQKVIQRA QKAGLPAHLI
      241 PDEITSVSVS ADVDAENTLR TAVLDFIDRL RCAERAIAVA RRGSNVAEQL DVTPLGVITE
      301 QEWLAHWPTA VNDSRGGSKK RKGMR
//