LOCUS SIT99648.1 325 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Nucleoside triphosphate pyrophosphohydrolase MazG (EC protein. ACCESSION LT708304-1060 PROTEIN_ID SIT99648.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="mazG" /locus_tag="BQ2027_MB1049" /EC_number="3.6.1.8" /note="Mb1049, -, len: 325 aa. Equivalent to Rv1021, len: 325 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 325 aa overlap). Conserved hypothetical protein, similar to YBL1_STRCI|P33653 hypothetical 26.1 kd protein from Streptomyces cacaoi (242 aa), FASTA scores: opt: 493, E(): 1.1e-23, (42.9% identity in 238 aa overlap). Protein product from Mb1049 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1049 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR004518" /db_xref="InterPro:IPR011551" /db_xref="UniProtKB/TrEMBL:A0A1R3XX33" BEGIN 1 MIVVLVDPRR PTLVPVEAIE FLRGEVQYTE EMPVAVPWSL PAARSAHAGN DAPVLLSSDP 61 NHPAVITRLA AGARLISAPD SQRGERLVDA VAMMDKLRTA GPWESEQTHD SLRRYLLEET 121 YELLDAVRSG SVDQLREELG DLLLQVLFHA RIAEDASQSP FTIDDVADTL MRKLGNRAPG 181 VLAGESISLE DQLAQWEAAK ASEKARKSVA DDVHTGQPAL ALAQKVIQRA QKAGLPAHLI 241 PDEITSVSVS ADVDAENTLR TAVLDFIDRL RCAERAIAVA RRGSNVAEQL DVTPLGVITE 301 QEWLAHWPTA VNDSRGGSKK RKGMR //