LOCUS       SIT99646.1               197 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
            protein.
ACCESSION   LT708304-1058
PROTEIN_ID  SIT99646.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1047"
                     /note="Mb1047, -, len: 197 aa. Equivalent to Rv1019, len:
                     197 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 197 aa overlap). Probable
                     transcriptional regulator, similar to many memebers of the
                     tetR family e.g. MTCY7D11.18c (34.4% identity in 189 aa
                     overlap). Helix turn helix motif from aa 27-48 (+5.42 SD).
                     Protein product from Mb1047 detected using shotgun mass
                     spectrometry. Mb1047 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XX46"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR023772"
                     /db_xref="InterPro:IPR036271"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XX46"
BEGIN
        1 MTGTERRHQL IGIARSLFAE RGYDGTSIEE IAQRANVSKP VVYEHFGGKE GLYAVVVDRE
       61 MSALLDGITS SLTNNRSRVR VERVALALLT YVEERTDGFR IMIRDSPASI SSGTYSSLLN
      121 DAVSQVSSIL AGDFARRGLD PDLAPLYAQA LVGSVSMTAQ WWLDAREPKK EVVAAHLVNL
      181 VWNGLTHLEA DPRLQDE
//