LOCUS SIT99646.1 197 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) protein. ACCESSION LT708304-1058 PROTEIN_ID SIT99646.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1047" /note="Mb1047, -, len: 197 aa. Equivalent to Rv1019, len: 197 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 197 aa overlap). Probable transcriptional regulator, similar to many memebers of the tetR family e.g. MTCY7D11.18c (34.4% identity in 189 aa overlap). Helix turn helix motif from aa 27-48 (+5.42 SD). Protein product from Mb1047 detected using shotgun mass spectrometry. Mb1047 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XX46" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="InterPro:IPR036271" /db_xref="UniProtKB/TrEMBL:A0A1R3XX46" BEGIN 1 MTGTERRHQL IGIARSLFAE RGYDGTSIEE IAQRANVSKP VVYEHFGGKE GLYAVVVDRE 61 MSALLDGITS SLTNNRSRVR VERVALALLT YVEERTDGFR IMIRDSPASI SSGTYSSLLN 121 DAVSQVSSIL AGDFARRGLD PDLAPLYAQA LVGSVSMTAQ WWLDAREPKK EVVAAHLVNL 181 VWNGLTHLEA DPRLQDE //