LOCUS SIT99627.1 205 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Alkylated DNA repair protein AlkB protein. ACCESSION LT708304-1039 PROTEIN_ID SIT99627.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1027C" /note="Mb1027c, -, len: 205 aa. Equivalent to Rv1000c, len: 205 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 205 aa overlap). Conserved hypothetical protein, equivalent to ML0190|NP_301263.1|NC_002677 conserved hypothetical protein from Mycobacterium leprae (205 aa). Also highly similar to SC5F8.12c|CAB93740.1|AL357613 hypothetical protein from Streptomyces coelicolor (210 aa), FASTA scores: E(): 2.1e-45, (56.8% identity); 9106290|AAF84108.1|AE003963_5|NP_298588.1|NC_002488 protein described as DNA repair system specific for alkylated DNA from Xylella fastidiosa (200 aa), FASTA scores: E(): 3.4e-14, (38.55% identity); and similar in C-terminus to other hypothetical proteins. Note that replaces original Rv1000 predicted on other strand. Mb1027c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XX27" /db_xref="InterPro:IPR005123" /db_xref="InterPro:IPR027450" /db_xref="InterPro:IPR032854" /db_xref="InterPro:IPR037151" /db_xref="UniProtKB/TrEMBL:A0A1R3XX27" BEGIN 1 MCDKLGGVAI AVQGALFEHN ERRQLGDGAF IDIRSGWLTG GEELLDALLS TVPWRAERRQ 61 MYDRVVDVPR LVSFHDLTIE DPPHPQLARM RRRLNDIYGG ELGEPFTTAG LCYYRDGSDS 121 VAWHGDTIGR GSTEDTMVAI VSLGATRVFA LRPRGRGPSL RLPLAHGDLL VMGGSCQRTF 181 EHAVPKTSAP TGPRVSIQFR PRDVR //