LOCUS       SIT99627.1               205 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Alkylated
            DNA repair protein AlkB protein.
ACCESSION   LT708304-1039
PROTEIN_ID  SIT99627.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1027C"
                     /note="Mb1027c, -, len: 205 aa. Equivalent to Rv1000c,
                     len: 205 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 205 aa overlap). Conserved hypothetical
                     protein, equivalent to ML0190|NP_301263.1|NC_002677
                     conserved hypothetical protein from Mycobacterium leprae
                     (205 aa). Also highly similar to
                     SC5F8.12c|CAB93740.1|AL357613 hypothetical protein from
                     Streptomyces coelicolor (210 aa), FASTA scores: E():
                     2.1e-45, (56.8% identity);
                     9106290|AAF84108.1|AE003963_5|NP_298588.1|NC_002488
                     protein described as DNA repair system specific for
                     alkylated DNA from Xylella fastidiosa (200 aa), FASTA
                     scores: E(): 3.4e-14, (38.55% identity); and similar in
                     C-terminus to other hypothetical proteins. Note that
                     replaces original Rv1000 predicted on other strand.
                     Mb1027c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XX27"
                     /db_xref="InterPro:IPR005123"
                     /db_xref="InterPro:IPR027450"
                     /db_xref="InterPro:IPR032854"
                     /db_xref="InterPro:IPR037151"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XX27"
BEGIN
        1 MCDKLGGVAI AVQGALFEHN ERRQLGDGAF IDIRSGWLTG GEELLDALLS TVPWRAERRQ
       61 MYDRVVDVPR LVSFHDLTIE DPPHPQLARM RRRLNDIYGG ELGEPFTTAG LCYYRDGSDS
      121 VAWHGDTIGR GSTEDTMVAI VSLGATRVFA LRPRGRGPSL RLPLAHGDLL VMGGSCQRTF
      181 EHAVPKTSAP TGPRVSIQFR PRDVR
//