LOCUS       SIT99611.1               248 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ADHESION COMPONENT TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER
            protein.
ACCESSION   LT708304-1023
PROTEIN_ID  SIT99611.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1012"
                     /note="Mb1012, -, len: 248 aa. Equivalent to Rv0986, len:
                     248 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 248 aa overlap). Probable ATP-binding
                     protein ABC transporter supposed involved in transport of
                     adhesion component (see citation below), highly similar to
                     many ATP-binding proteins e.g. AE0010|AE001033_8 ABC
                     transporter ATP-binding protein from Archaeoglobus
                     fulgidus (228 aa), FASTA scores: opt: 669, E(): 0, (45.7%
                     identity in 219 aa overlap); CAB81857.1|AL161691 putative
                     ABC-transporter ATP-binding protein from Streptomyces
                     coelicolor (246 aa); X84019|ZMDNAGRP_4 glutamate uptake
                     regulatory protein (grp) from Z.mobilis (232 aa), FASTA
                     score: (44.4% identity in 225 aa overlap);
                     Z99111|BSUB0008_108 from Bacillus subtilis (230 aa), FASTA
                     score: (38.7% identity in 222 aa overlap); etc. Contains
                     PS00017 ATP/GTP-binding site motif A (P-loop), and PS00211
                     ABC transporters family signature. BELONGS TO THE
                     ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).
                     Protein product from Mb1012 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1012 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XX09"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XX09"
BEGIN
        1 MNRQPIVQLS NLSWTFREGE TRRQVLDHIT FDFEPGEFVA LLGQSGSGKS TLLNLISGIE
       61 KPTTGDVTIN GFAITQKTER DRTLFRRDQI GIVFQFFNLI PTLTVLENIT LPQELAGVSQ
      121 RKAAVVARDL LEKVGMADRE RTFPDKLSGG EQQRVAISRA LAHNPMLVLA DEPTGNLDSD
      181 TGDKVLDVLL DLTRQAGKTL IMATHSPSMT QHADRVVNLQ GGRLIPALNR ENQTDQPAST
      241 ILLPTSYE
//