LOCUS SIT99577.1 303 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN protein. ACCESSION LT708304-989 PROTEIN_ID SIT99577.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0979" /note="Mb0979, -, len: 303 aa. Equivalent to Rv0954, len: 303 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 303 aa overlap). Probable conserved transmembrane protein, highly similar to 34KD_MYCPA|Q04959 34 kd antigenic protein from Mycobacterium paratuberculosis (298 aa), FASTA scores: opt: 1023, E(): 7.2e-36, (59.3% identity in 305 aa overlap); AAC69251.1|U82111 34 kDa antigen precursor from Mycobacterium leprae (336 aa); and AL035500|MLCL373.06 hypothetical membrane protein from Mycobacterium leprae (297 aa), FASTA score: (55.6% identity in 315 aa overlap). Protein product from Mb0979 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0979 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P65638" /db_xref="InterPro:IPR035166" /db_xref="UniProtKB/Swiss-Prot:P65638" BEGIN 1 MTYSPGNPGY PQAQPAGSYG GVTPSFAHAD EGASKLPMYL NIAVAVLGLA AYFASFGPMF 61 TLSTELGGGD GAVSGDTGLP VGVALLAALL AGVALVPKAK SHVTVVAVLG VLGVFLMVSA 121 TFNKPSAYST GWALWVVLAF IVFQAVAAVL ALLVETGAIT APAPRPKFDP YGQYGRYGQY 181 GQYGVQPGGY YGQQGAQQAA GLQSPGPQQS PQPPGYGSQY GGYSSSPSQS GSGYTAQPPA 241 QPPAQSGSQQ SHQGPSTPPT GFPSFSPPPP VSAGTGSQAG SAPVNYSNPS GGEQSSSPGG 301 APV //