LOCUS       SIT99567.1               158 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FAPY-DNA GLYCOSYLASE)
            protein.
ACCESSION   LT708304-979
PROTEIN_ID  SIT99567.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0969"
                     /note="Mb0969, -, len: 158 aa. Equivalent to Rv0944, len:
                     158 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 158 aa overlap). Possible
                     formamidopyrimidine-DNA glycosylase (EC 3.2.2.23), similar
                     to C-terminus of formamidopyrimidine-DNA glycosylases e.g.
                     CAB63194.1|AL133469 putative formamidopyrimidine-DNA
                     glycosylase from Streptomyces coelicolor (287 aa);
                     FPG_LACLA|NP_266509.1|NC_002662 formamidopyrimidine-DNA
                     glycosylase (EC 3.2.2.23) from Lactococcus lactis subsp.
                     lactis (273 aa), FASTA scores: opt: 246, E(): 2.4e-09,
                     (28.9% identity in 142 aa overlap);
                     O50606|FPG_THETH|MUTM|FPG FORMAMIDOPYRIMIDINE-DNA
                     GLYCOSYLASE from Thermus thermophilus (267 aa); etc. Also
                     similar to C-termini of endonucleases or DNA glycosylases
                     of Mycobacterium tuberculosis e.g. Rv3297, Rv2464c,
                     Rv2924c. MAY BE BELONG TO THE FPG FAMILY. Mb0969 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XWW9"
                     /db_xref="InterPro:IPR000214"
                     /db_xref="InterPro:IPR010663"
                     /db_xref="InterPro:IPR010979"
                     /db_xref="InterPro:IPR015886"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWW9"
BEGIN
        1 MAGTPQPRAL GPDALDVSTD DLAGLLAGNT GRIKTVITDQ KVIAGIGNAY SDEILHVAKI
       61 SPFATAGKLS GAQLTCLHEA MASVLSDAVR RSVGQGAAML KGEKRSGLRV HARTGLPCPV
      121 CGDTVREVSF ADKSFQYCPT CQTGGKALAD RRMSRLLK
//