LOCUS       SIT99557.1               374 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PERIPLASMIC
            PHOSPHATE-BINDING LIPOPROTEIN PSTS1 (PBP-1) (PSTS1) protein.
ACCESSION   LT708304-969
PROTEIN_ID  SIT99557.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pstS1"
                     /locus_tag="BQ2027_MB0959"
                     /standard_name="phoS1; phoS"
                     /note="Mb0959, pstS1, len: 374 aa. Equivalent to Rv0934,
                     len: 374 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 374 aa overlap). pstS1 (previously
                     known as phoS1 or phoS), phosphate-binding lipoprotein
                     component of inorganic phosphate transport system (see
                     first, fourth, fifth and sixth citations below), highly
                     similar to Rv0932c|MTCY08D9.07|pstS2 PHOSPHATE-BINDING
                     PERIPLASMIC LIPOPROTEIN from Mycobacterium tuberculosis
                     (370 aa), FASTA scores: opt: 460, E(): 5.9e-19, (31.2%
                     identity in 375 aa overlap); and Rv0928|MTCY21C12.22|pstS3
                     PHOSPHATE-BINDING PERIPLASMIC LIPOPROTEIN from
                     Mycobacterium tuberculosis (374 aa), FASTA scores: opt:
                     435, E():1.1e-17, (30.0% identity in 380 aa overlap)
                     (Mycobacterium tuberculosis seems to have three PstS-like
                     proteins, others being Rv0932c and Rv0928c). Also highly
                     similar to MTCY08D9.05c|P15712|PAB_MYCTU PROTEIN ANTIGEN B
                     PRECURSOR from Mycobacterium tuberculosis (374 aa), FASTA
                     scores: opt: 2459, E(): 0, (100% identity in 374 aa
                     overlap). Contains a prokaryotic membrane lipoprotein
                     lipid attachment site (PS00013) at the N-terminus so the
                     23 aa leader peptide sequence is probably removed. BELONGS
                     TO FAMILY OF PHOSPHATE RECEPTORS FOR BACTERIAL ABC-TYPE
                     LIPOPROTEIN TRANSPORTERS. Protein product from Mb0959
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb0959 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XWV8"
                     /db_xref="InterPro:IPR005673"
                     /db_xref="InterPro:IPR024370"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWV8"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MKIRLHTLLA VLTAAPLLLA AAGCGSKPPS GSPETGAGAG TVATTPASSP VTLAETGSTL
       61 LYPLFNLWGP AFHERYPNVT ITAQGTGSGA GIAQAAAGTV NIGASDAYLS EGDMAAHKGL
      121 MNIALAISAQ QVNYNLPGVS EHLKLNGKVL AAMYQGTIKT WDDPQIAALN PGVNLPGTAV
      181 VPLHRSDGSG DTFLFTQYLS KQDPEGWGKS PGFGTTVDFP AVPGALGENG NGGMVTGCAE
      241 TPGCVAYIGI SFLDQASQRG LGEAQLGNSS GNFLLPDAQS IQAAAAGFAS KTPANQAISM
      301 IDGPAPDGYP IINYEYAIVN NRQKDAATAQ TLQAFLHWAI TDGNKASFLD QAHFQPLPPA
      361 VVKLSDALIA TISS
//