LOCUS SIT99551.1 304 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER PSTA1 protein. ACCESSION LT708304-963 PROTEIN_ID SIT99551.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="pstA1" /locus_tag="BQ2027_MB0953" /note="Mb0953, pstA1, len: 304 aa. Equivalent to Rv0930, len: 304 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 304 aa overlap). Probable pstA1, phosphate-transport integral membrane ABC transporter (see citation below), highly similar to others e.g. NP_302393.1|NC_002677 membrane-bound component of phosphate transport from Mycobacterium leprae (304 aa); CAB88473.1|AL353816 phosphate ABC transport system permease protein from Streptomyces coelicolor (354 aa) (N-terminus longer); NP_312689.1|NC_002695 phosphate transport system permease protein PstA from Escherichia coli strain O157:H7 (296 aa); etc. Also similar to Rv0936|MTCY08D9.03c|PSTA2 PROBABLE TRANSMEMBRANE ABC TRANSPORTER COMPONENT OF PHOSPHATE UPTAKE SYSTEM from Mycobacterium tuberculosis (301 aa). Mb0953 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XWV3" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR005672" /db_xref="InterPro:IPR035906" /db_xref="UniProtKB/TrEMBL:A0A1R3XWV3" BEGIN 1 MSPSTSIEAL DQPVKPVVFR PLTLRRRIKN SVATTFFFTS FVVALIPLVW LLWVVIARGW 61 FAVTRSGWWT HSLRGVLPEQ FAGGVYHALY GTLVQAGVAA VLAVPLGLMT AVYLVEYGTG 121 RMSRVTTFTV DVLAGVPSIV AALFVFSLWI ATLGFQQSAF AVALALVLLM LPVVVRAGEE 181 MLRLVPDELR EASYALGVPK WKTIVRIVAP IAMPGIVSGI LLSIARVVGE TAPVLVLVGY 241 SHSINLDVFH GNMASLPLLI YTELTNPEHA GFLRVWGAAL TLIIVVATIN LAAAMIRFVA 301 TRRR //