LOCUS       SIT99551.1               304 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER
            PSTA1 protein.
ACCESSION   LT708304-963
PROTEIN_ID  SIT99551.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pstA1"
                     /locus_tag="BQ2027_MB0953"
                     /note="Mb0953, pstA1, len: 304 aa. Equivalent to Rv0930,
                     len: 304 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 304 aa overlap). Probable pstA1,
                     phosphate-transport integral membrane ABC transporter (see
                     citation below), highly similar to others e.g.
                     NP_302393.1|NC_002677 membrane-bound component of
                     phosphate transport from Mycobacterium leprae (304 aa);
                     CAB88473.1|AL353816 phosphate ABC transport system
                     permease protein from Streptomyces coelicolor (354 aa)
                     (N-terminus longer); NP_312689.1|NC_002695 phosphate
                     transport system permease protein PstA from Escherichia
                     coli strain O157:H7 (296 aa); etc. Also similar to
                     Rv0936|MTCY08D9.03c|PSTA2 PROBABLE TRANSMEMBRANE ABC
                     TRANSPORTER COMPONENT OF PHOSPHATE UPTAKE SYSTEM from
                     Mycobacterium tuberculosis (301 aa). Mb0953 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XWV3"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR005672"
                     /db_xref="InterPro:IPR035906"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWV3"
BEGIN
        1 MSPSTSIEAL DQPVKPVVFR PLTLRRRIKN SVATTFFFTS FVVALIPLVW LLWVVIARGW
       61 FAVTRSGWWT HSLRGVLPEQ FAGGVYHALY GTLVQAGVAA VLAVPLGLMT AVYLVEYGTG
      121 RMSRVTTFTV DVLAGVPSIV AALFVFSLWI ATLGFQQSAF AVALALVLLM LPVVVRAGEE
      181 MLRLVPDELR EASYALGVPK WKTIVRIVAP IAMPGIVSGI LLSIARVVGE TAPVLVLVGY
      241 SHSINLDVFH GNMASLPLLI YTELTNPEHA GFLRVWGAAL TLIIVVATIN LAAAMIRFVA
      301 TRRR
//