LOCUS       SIT99547.1               358 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Oxidoreductase
            protein.
ACCESSION   LT708304-959
PROTEIN_ID  SIT99547.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0949C"
                     /note="Mb0949c, -, len: 358 aa. Equivalent to Rv0926c,
                     len: 358 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 358 aa overlap). Conserved hypothetical
                     protein, similar to Rv1059 CONSERVED HYPOTHETICAL PROTEIN
                     from Mycobacterium tuberculosis (354 aa). Also shows some
                     similarity to AF170923|AF170923_3 dihydrodipicolinate
                     reductase from Mastigocladus laminosus (278 aa), FASTA
                     scores: opt: 170, E(): 0.00088, (25.7% identity in 276 aa
                     overlap). Protein product from Mb0949c detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb0949c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWU8"
BEGIN
        1 MAIPVVQLGT GNVGVHSLRA LIADPEFELT GVWVSSDAKA GKDAAELAGL ADSTGVRAST
       61 DLNAVLATGP RCAVYNAMAD NRLPEALEDY RRILAAGINI VGSGPVFLQY PWQVIPDEII
      121 KPLQDAARAG NSSLYVNGID PGFANDLLPM ALAGTCESIE QIRCMEIVDY ATYDSAVVMF
      181 DVMGFGKPMD QIPMLLQPGV LSLAWGSVVR QLAAGLGISL DGVEEMYVRE PAPEAFNIAS
      241 GHIPKGSAAA LRFEVLGLVD GVPAVVLEHV TRLRADLCPE WPQPAQPGGS YRIEISGEPC
      301 YAMDICLSSR HGDHNHAGLV ATAMRIVNAI PAVVAAEPGI RTTLDLPLIT GEGRYAAA
//