LOCUS SIT99547.1 358 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Oxidoreductase protein. ACCESSION LT708304-959 PROTEIN_ID SIT99547.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0949C" /note="Mb0949c, -, len: 358 aa. Equivalent to Rv0926c, len: 358 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 358 aa overlap). Conserved hypothetical protein, similar to Rv1059 CONSERVED HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (354 aa). Also shows some similarity to AF170923|AF170923_3 dihydrodipicolinate reductase from Mastigocladus laminosus (278 aa), FASTA scores: opt: 170, E(): 0.00088, (25.7% identity in 276 aa overlap). Protein product from Mb0949c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0949c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR036291" /db_xref="UniProtKB/TrEMBL:A0A1R3XWU8" BEGIN 1 MAIPVVQLGT GNVGVHSLRA LIADPEFELT GVWVSSDAKA GKDAAELAGL ADSTGVRAST 61 DLNAVLATGP RCAVYNAMAD NRLPEALEDY RRILAAGINI VGSGPVFLQY PWQVIPDEII 121 KPLQDAARAG NSSLYVNGID PGFANDLLPM ALAGTCESIE QIRCMEIVDY ATYDSAVVMF 181 DVMGFGKPMD QIPMLLQPGV LSLAWGSVVR QLAAGLGISL DGVEEMYVRE PAPEAFNIAS 241 GHIPKGSAAA LRFEVLGLVD GVPAVVLEHV TRLRADLCPE WPQPAQPGGS YRIEISGEPC 301 YAMDICLSSR HGDHNHAGLV ATAMRIVNAI PAVVAAEPGI RTTLDLPLIT GEGRYAAA //